Skin Signs of Systemic Disease

Question 1

Answer 1

Heliotrope Sign (associated with Dermatomyositis**)

• ​dermatomyositis = autoimmune disease that leads to degeneration of the skin and muscle
  
  • characterized by muscle weakness heliotrope sign and Gottron’s Papules

Question 2

Answer 2

Gottron’s Papules (indicative of Dermatomyositis**)

• dermatomyositis = autoimmune disorder that leads to the degeneration of the skin and muscle
  
  • characterized by muscle weakness and Gottron’s papules and Heliotrope sign
• Gottron’s papules = over the joints of the hands

Question 3

Answer 3

Butterfly/Malar Rash

• indicative of Systemic Lupus Erythematosus
  
  • worsened when exposed to the sunlight
• systemic lupus erythematosus also will show a rash on the hands that spares the knuckles

Question 4

Answer 4

Mycosis Fungoides (indicative of cutaneous T-Cell Lymphoma)

• often looks like psoriasis when in the plaque stage
  
  • if something looks like psoriasis or a tinea infection but is NOT RESPONDING TO TX consider Cutaneous T-Cell Lymphoma