Skin infections Flashcards
Most common causes of cellulitis
oupatients
1-strep pyogenes
2-S. aureus
3-other strep-rare
Cellulitis causes inpatient
- gram negative organisms: E. Coli, klebsiella, pseudomonas, enterobacter
- S. aureus (Mrsa or Ca-MRSA?)
- Strep
Ca-MRSA
bactrim
doxy
clinda
what covers strep and ca-MRSA staph?
Clindamycin.
bactrim and doxy will cover staph MRSA but unlikely to also cover strep. would need 2nd agent like Keflex or beta lactam
Ipecac good for:
immediate “at home” ingestions of solid** ingestions. not used as routinely in emergency settings because of delay in being able to use charcoal (prolonged vomiting)
what is your drug of choice for benzo overdose?
Flumazinole
when is gastric lavage used for OD?
when ingestions > 30min ago. pill fragments may be hard to remove
activated charcoal for OD
1g/kg mixed with water. repeat doses q 4 hours. 1st dose most effective when combined with a cathartic such as sorbitol
Acetaminophen OD S&S
around 24-48 hrs N/V
RUQ pain
hepatotoxicity signs
Acetaminophen OD tx
- emesis for recent ingestions: gastric lavage/activated charcoal
- N-Acetylcysteine*** (mucomyst)
Salicylate Intoxication S/S
N/v
- Tinnitis, dizziness, HA
- dehydration
- hyperthermia
- apnea, cyanosis, metabolic acidosis
- Elevated LFTs
Salicylate treatment
- gastric lavage/charcoal (emesis)
- sodium bicarb IV to correct severe acidosis
severe acidosis is
<7.1
oxyhemoglobulin dissociation curve. what happens in acidosis
-Right shift
oragnophosphate (insectacide) poisoning. Malathion or parathioon. S&S
blurred vision and miosis**
bradycardia**
excessive salvation
mental confusion
miosis is
constriction
mydriasis is
dilation
Drugs that tend to sedate cause
constrictive pupils (miosis)
upper drugs tend to:
dilate (mydriasis)
Management for insecticide poisoning
wash skin thoroughly
- charcoal if ingested
- Atropine for organophosphate toxicity**
Antidepressant toxicity S&S
confusion, hallucinations
- urinary retention
- hypotension, tachy
- hypothermia**
- seizures
Management of Antidepressant OD
-ICu if CNS or cardiac toxicity
-gastric lavage/charcoal
-NaHco3 to counter dysrhythmias and maintain pH
-benzodiazepine IV to control seizures***
Serotonin syndrome: treated with dantrolene; clonazepam used to tx rigor, cooling blankets for temperature
Narcotic toxicity tx
- emetic contraindicated
- narcan
- stadol
Benzo OD S&S
slurred speech
hyporeflexia
Transplant failure s/s and treatment
- flu picture
- immediate biopsy
Transplant anti-rejection drugs
standard therpy is a calcineurin inhibitor + antimetabolite + steroid
Calcineurin inhibitor: prograft
antimetabolite: cellcept
Herpes Zoster wtih eruptions of vesicles, erythema with exudate
typical presentation of zoster