Skin Infections Flashcards
Which tetracycline may cause irreversible pigmentation and possibly discolouration of the conjunctiva as well?
Minocycline
Mupirocin and fusidic acid (for skin infections) should be used for maximum ____ days
10 days
To avoid development of resistance
How long should topical antifungals be continued after infection clears
1 - 2 weeks
To prevent relapse
True or false:
Topical therapy is more effective than systemic therapy in treating fungal nail infections
FALSE
Systemic therapy is more effective
Ring worm infection on what part of the body requires systemic treatment ?
On the scalp (tinea capitis)
All other forms can be treated topically
What is pityriasis versicolor
- Sometimes called tinea versicolor
- Common fungal infection that causes small patches of skin to become scaly and discoloured.
- Patches of skin may be darker or lighter than your normal skin colour, or may be red, brown or pink.
Treatment for tinea versicolor
3 options
Ketoconazole shampoo , Topical imidazoles or topical terbinafine
True or false:
Frequent and liberal use of emollients mean less steroid cream is needed
TRUE
Emollients increase the efficacy of topic steroids and have a steroid sparing action
True or false:
Aqueous cream is generally not recommended in eczema
TRUE
There is a high risk of developing skin reactions
Which drugs may exacerbate psoriasis ?
5 points
1) Lithium
2) ACE inhibitors
3) NSAIDs
4) Beta blockers
5) Chloroquine and Hydroxychloroquine
Consecutive use of topical corticosteroids in psoriasis should not exceed ______
(or ______ for very potent topical steroids)
8 weeks
4 weeks if very potent
As it may lead to irreversible skin atrophy. Can restart after a 4 week treatment break
Which is the more potent hydrocortisone ?
Acetate or Butyrate
Hydrocortisone butyrate (Locoid) is a potent topical corticosteroid
Hydrocortisone acetate (available OTC) is a mild topical steroid
Dermovate potency
Very potent
Active ingredient is clobetasol
Eumovate potency
Moderate potency
Active ingredient is clobetasone
Available OTC
Treatment options for hyperhidrosis?
3 points
a) 1st line Aluminium chloride hexahydrate
b) In severe cases: Glycopyrronium Br solutions (specialist)
c) Last line: Botox (botulinum toxin A)
Pruritis is common in primary billiary cirrhosis and drug induced cholestasis.
How is this treated
Use colestyramine
What class of drug is adapalene
It is a retinoid like drug
Maximum improvement with oral antibacterials for acne is usually seen after _____
4-6 months
Why is minocycline not generally used as oral treatment of acne while other drugs in its class are? (2 points)
May cause irreversible pigmentation
Greater risk of lupus erythematous like sydrome
How long is oral isotretinoin usually given for acne
At least 16 weeks
Repeated courses not usually needed
What treatment options are available for actinic (solar) keratosis
(3 points)
Diclofenac 3 % gel (solaraze)
Flourouracil cream (can combine with salicylic acid)
Imiquimod (for face and scalp lesions when other treatments can’t be used)
Which strains of HPV cause warts
6 and 11
Strains 16 and 18 commonly cause cervical cancer
Most warts will resolve spontaneously within ________
Genital warts may resolve spontaneously within _______
2 years
6 months
True or false:
Facial warts should be referred for specialist treatment
TRUE
Treatment options of ano-genital warts
3 points
- Topical podophyllotoxin
- Topical imiquimod
- Cryotherapy
