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PATHOLOGY | SKIN > SKIN - GOLJAN > Flashcards

SKIN - GOLJAN Flashcards

1
Q

acantholysis

seen in?

A

loss of cohesion in keratinocytes

pemphigus vulgaris

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2
Q

common wart AKA

A

verruca vulgaris

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3
Q

persistence of nuclei in stratum corneum layer

A

parakeratosis

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4
Q

what type of virus is MOLLUSCUM CONTAGIOSUM

describe the lesion

A

DNA poxvirus

bowl shaped. central depression filled w/ keratin
the depression contain viral particles called molluscum
bodies

the molluscum bodies appear as ELLIPSOID CYTOPLASMIC INCLUSIONS

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5
Q

define : nevus

A

ANY skin lesion

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6
Q

define : nevocellular nevus

A

neoplasm of neural crest-derived nevus cells ( modified melanocytes )

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7
Q

compare maturation level in melanoma vs nevus

A

melanoma - little or no maturation

nevus - lots of maturation

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8
Q

melanoma growth patterns

A

radial - linear - NO metastatic potential

vertical - metastatic potential

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9
Q

type of RADIAL MELANOMAS

A
  1. superficial spreading melanoma - SSM
  2. lentigo meligna melanoma
  3. nodular melanoma
  4. acral lentiginuous melanoma
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10
Q

which melanoma is unrelated to sun exposure

A

acral lentiginuous melanoma

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11
Q

rapid increase in # of keratoses

A

Leser-Trelat sign

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12
Q

Leser-Trelat sign

A

STOMACH ADENOCARCINOMA

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13
Q

velvety pigmented lesion in axilla

A

acanthosis nigricans (AN)

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14
Q

*cause of acanthosis nigricans

A

excess insulin

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15
Q

what is another phenotypic skin marker for gastric cancer

A

ananthosis nigricans

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16
Q

precursor of SCC

A

actinic ( solar ) keratosis

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17
Q

MC malignant skin tumor

A

basal cell carcinoma ( BCC )

18
Q

describe : actinic keratosis

A

hyperkeratotic, pearly gray white appearance

*recurs when scraped off

19
Q

location of BCC vs SCC

A

BCC upper lip and above

SCC lower lip

20
Q

superficial fungal infection AKA
what location in skin
general causative agent

A

superficial mycoses -
stratum corneum
dermatophytes

21
Q

superficial fungal infection of

  1. scalp
  2. body
  3. groin
  4. foot
  5. nail
A

all TINEA

  1. capitis
  2. corporis
  3. cruris
  4. pedis
  5. unguium AKA onychomycosis
22
Q

tinea versicolor caused by

A

malassezia furfur

23
Q

impetigo caused by

A

MC-staph aureus

2nd is strep pyogenes

24
Q

morphological finding in IMPETIGO

A

neutrophils beneath the stratum corneum

25
two types of impetigo
impetigo bullosa | impetigo contagiosa
26
type of rash in impetigo
red macules become multiple pustules which break and crust over HONEY COLORED CRUST
27
what do the bacteria do in impetigo
they make toxin against DESMOGLEIN 1, which is responsible for cell to cell adhesion in the epidermis.
28
difference in spots in RUBELLA vs RUBEOLA
RUBEOLA - measles - KOPLIK spots - white spots in buccal mucosa RUBELLA - german measles - FORCHHEIMER spots - red spots on soft\hard palate
29
common wart AKA
verruca vulgaris
30
where does the rash begin in rubella
at the hairline and extends down the face | -red maculopapular rash
31
which HPV is related to SCC
HPV 5+8
32
which HPV is related to anogenital warts
HPV 6+11
33
inflammatory reaction in the SUBQ fat is AKA
panniculitis
34
MC form of panniculitis
erythema nodosum (EN)
35
describe EN
painful, red nodules and plaques on ANTERIOR SHIN after weeks, the lesions flatten and become BRUISELIKE
36
define : rhinophyma
enlargement of the nose
37
rhinophyma seen in which skin condition
acne ROSACEA
38
describe ROSACEA
inflammation of pilosebaceous unit of facial skin flushing + pustules + telangiectasia RHINOPHYMA
39
define : ichthyosis
excessive cornification of skin, giving it a scaly appearance
40
define : hypertrichosis
excessive hairiness due to increased hair follicles

PATHOLOGY | SKIN (1 decks)

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