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PATHOLOGY | SKIN > SKIN - GOLJAN > Flashcards

SKIN - GOLJAN Flashcards

1
Q

acantholysis

seen in?

A

loss of cohesion in keratinocytes

pemphigus vulgaris

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2
Q

common wart AKA

A

verruca vulgaris

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3
Q

persistence of nuclei in stratum corneum layer

A

parakeratosis

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4
Q

what type of virus is MOLLUSCUM CONTAGIOSUM

describe the lesion

A

DNA poxvirus

bowl shaped. central depression filled w/ keratin
the depression contain viral particles called molluscum
bodies

the molluscum bodies appear as ELLIPSOID CYTOPLASMIC INCLUSIONS

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5
Q

define : nevus

A

ANY skin lesion

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6
Q

define : nevocellular nevus

A

neoplasm of neural crest-derived nevus cells ( modified melanocytes )

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7
Q

compare maturation level in melanoma vs nevus

A

melanoma - little or no maturation

nevus - lots of maturation

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8
Q

melanoma growth patterns

A

radial - linear - NO metastatic potential

vertical - metastatic potential

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9
Q

type of RADIAL MELANOMAS

A
  1. superficial spreading melanoma - SSM
  2. lentigo meligna melanoma
  3. nodular melanoma
  4. acral lentiginuous melanoma
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10
Q

which melanoma is unrelated to sun exposure

A

acral lentiginuous melanoma

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11
Q

rapid increase in # of keratoses

A

Leser-Trelat sign

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12
Q

Leser-Trelat sign

A

STOMACH ADENOCARCINOMA

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13
Q

velvety pigmented lesion in axilla

A

acanthosis nigricans (AN)

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14
Q

*cause of acanthosis nigricans

A

excess insulin

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15
Q

what is another phenotypic skin marker for gastric cancer

A

ananthosis nigricans

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16
Q

precursor of SCC

A

actinic ( solar ) keratosis

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17
Q

MC malignant skin tumor

A

basal cell carcinoma ( BCC )

18
Q

describe : actinic keratosis

A

hyperkeratotic, pearly gray white appearance

*recurs when scraped off

19
Q

location of BCC vs SCC

A

BCC upper lip and above

SCC lower lip

20
Q

superficial fungal infection AKA
what location in skin
general causative agent

A

superficial mycoses -
stratum corneum
dermatophytes

21
Q

superficial fungal infection of

  1. scalp
  2. body
  3. groin
  4. foot
  5. nail
A

all TINEA

  1. capitis
  2. corporis
  3. cruris
  4. pedis
  5. unguium AKA onychomycosis
22
Q

tinea versicolor caused by

A

malassezia furfur

23
Q

impetigo caused by

A

MC-staph aureus

2nd is strep pyogenes

24
Q

morphological finding in IMPETIGO

A

neutrophils beneath the stratum corneum

25
Q

two types of impetigo

A

impetigo bullosa

impetigo contagiosa

26
Q

type of rash in impetigo

A

red macules become multiple pustules which break and crust over
HONEY COLORED CRUST

27
Q

what do the bacteria do in impetigo

A

they make toxin against DESMOGLEIN 1, which is responsible for cell to cell adhesion in the epidermis.

28
Q

difference in spots in RUBELLA vs RUBEOLA

A

RUBEOLA

  • measles
  • KOPLIK spots - white spots in buccal mucosa

RUBELLA

  • german measles
  • FORCHHEIMER spots - red spots on soft\hard palate
29
Q

common wart AKA

A

verruca vulgaris

30
Q

where does the rash begin in rubella

A

at the hairline and extends down the face

-red maculopapular rash

31
Q

which HPV is related to SCC

A

HPV 5+8

32
Q

which HPV is related to anogenital warts

A

HPV 6+11

33
Q

inflammatory reaction in the SUBQ fat is AKA

A

panniculitis

34
Q

MC form of panniculitis

A

erythema nodosum (EN)

35
Q

describe EN

A

painful, red nodules and plaques on
ANTERIOR SHIN

after weeks, the lesions flatten and become BRUISELIKE

36
Q

define : rhinophyma

A

enlargement of the nose

37
Q

rhinophyma seen in which skin condition

A

acne ROSACEA

38
Q

describe ROSACEA

A

inflammation of pilosebaceous unit of facial skin
flushing + pustules + telangiectasia
RHINOPHYMA

39
Q

define : ichthyosis

A

excessive cornification of skin, giving it a scaly appearance

40
Q

define : hypertrichosis

A

excessive hairiness due to increased hair follicles

PATHOLOGY | SKIN (1 decks)

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