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HISTOLOGY > SKIN - EPIDERMIS > Flashcards

SKIN - EPIDERMIS Flashcards

1
Q

What are the 3 layers of skin?

A
  • Epidermis at the top
  • Dermis
  • Hypodermis - sometimes classified as skin sometimes not
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2
Q

What are the 4 layers of the epidermis ( starting from top down?)

A
  • Stratum corner
  • Stratum granulosum
  • Stratum spinosum / Prickle layer
  • Stratum basale / Basal layer
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3
Q

What type of specialised cells are found in the epidermis? (2)

A
  • Keratinised stratified squamous epithelium
  • Mostly filled with keratinocytes
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4
Q

Which classification of cells are found in the stratum basale?

A
  • Cuboidal cells at the basal layer
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5
Q

Where is the stratum basale found?

A

Sat on the basement membrane

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6
Q

Which layer does mitosis occur in?

A

Stratum basale

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7
Q

How many layers of cells are in the stratum spinosum and what are they connected by?

A

8-10 layers of cells connected by desmosomes

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8
Q

What proteins does the stratum spinosum produce and what is their use?

A

Produces cytokeratins which help to form hair and nails

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9
Q

Which classification of cells are found in the spinosum layer?

A

Columnar

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10
Q

Which classification of cells are found in the stratum granulosum?

A

Squamous cells

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11
Q

How many layers of cells in stratum granulosum?

A

3-5 layers

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12
Q

What are the granules in the stratum granulosum packed with?

A

Keratohyalins

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13
Q

Which layer is keratin found in?

A

Stratum cornerum

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14
Q

What are the steps of keratin maturation in each layer?

A

Starting from the bottom:
- Stratum basale - mitosis and some cytokeratin
- Stratum spinosum - cytokeratin
-Stratum granulosum - keratohyalin granules
- Stratum corneum - keratin

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15
Q

What are the 5 layers of epidermis in thick skin?

A
  • Stratum basale
  • Stratum spinosum
  • Stratum granulosum
  • Stratum lucidum
  • Stratum corneum
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16
Q

Give two places where thick skin is found

A
  • Palms
  • Soles of feet
17
Q

Which classification of cell is the stratum corneum made from? (2)

A
  • Squames (dying keratinocytes)
  • Mature keratin
18
Q

Give 3 cell types in the epidermis and what they do

A
  • Melanocytes (stratum basale) - produce melanin
  • Merkel cell (stratum basale) - associated with free nerve endings and touch, sensory
  • Langerhan’s (all layers and dermis) - immune cells

HISTOLOGY (3 decks)

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