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Surgery > Skin, Breast > Flashcards

Skin, Breast Flashcards

1
Q

Bathing trunk distribution of nevus

A

Giant hairy nevus

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2
Q

Nevus that is the precursor of melanoma

A

Dysplastic nevus

BK mole

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3
Q

Most common skin malignancy

A

Basal cell CA

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4
Q

Waxy cream colored,rolled pearly borders

Palisading arrangement

A

Basal cell CA

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5
Q

Melanoma with best prognosis

A

Lentigo maligna

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6
Q

Melanoma that is the most common

A

Superficial spreading

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7
Q

Worst prognosis melanoma

A

Acral lentiginous

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8
Q

Pigmentation on the proximal or lateral nail fold

Diagnostic of subungual melanoma

A

Hutchinson sign

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9
Q

Rare but aggressive cutaneous malignancy arising from neuroendocrine cells

A

Merkel cell carcinoma

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10
Q

Tumors arising from areas of previous radiation or lymphedema

A

Angiosarcoma

Stewart-Treves syndrome

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11
Q

Kaposi sarcoma is primarily treated with

A

Radiation

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12
Q

Suckling neonate

MRSA

A

Epidemic puerperal mastitis

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13
Q

Chronic inflammatory condition of the nipple areola complex that originated from areolar glands?

A

Hidradenitis suppurativa

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14
Q

Level of axillary lymph nodes are based on this structure

A

Pectoralis minor

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15
Q

Most frequent site of breast cancer metastasis

A

Bone

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16
Q

True anatomic precursor of invasive ductal carcinoma

A

DCIS

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17
Q

Melanoma that may be confused with Paget disease

A

Superficial spreading

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18
Q

Intracytoplasmic mucin
Indian file arrangement

Type of breast CA

A

Lobular

Mucinous- extracellular pools of mucin

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19
Q

Single most important predictor of survival in breast cancer?

A

Axillary lymph node metastasis

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20
Q

Treatment for LCIS in breast

A

Observe

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21
Q

Treatment for DCIS in breast

A

Low grade-lumpectomy
Intermediate- lumpectomy and RT
High- mastectomy

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22
Q

Breast cancer treatment for pregnant patients in the 1st and 2nd trimester

A

MRM

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23
Q

Breast cancer treatment for pregnant patients in the 3rd trimester

A

BCS

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24
Q

Most common organism in human bites

A

Eikenella corrodens

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25
Q

Normal threhold for pressure injury

A

60mmHg for at least 1 hour

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26
Q

UV ray that is responsible for acute and chronic skin effects

A

UVB

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27
Q

UV ray that is absorbed by the ozone layer

A

UVC

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28
Q

Most common sites of necrotizing soft tissue infections

A

External genitalia, perineum, abdominal wall

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29
Q

Common sites of hidradenitis suppurativa

A

Axilla
Inguinal
Perianal

30
Q

Granulomatous suppurative bacterial disease
Presents as nodules and spread to form draining tracts

(+) sulfur granules

A

Actinomycosis

31
Q

Rapidly enlarging necrotic lesion with undermined border and surrounding erythema

Linked to IBD, RA, hematologic malignancy 50% of the time

A

Pyoderma gangrenosum

32
Q

Skin erythema, bullae formation and skin loss that happens in the granular layer

From exotoxin

A

SSSS

33
Q

Most common benign cyst in the skin

A

Epidermal

34
Q

Most common site of dermoid cyst in the skin

A

Eyebrows

35
Q

Benign Cyst that occurs in the scalp of females

Lacks a granular layer

A

Trichilemmal

36
Q

Yellow or light brown with velvety, greasy texture

Chest, back and abdomen of older individuals
Lesser-Trelat sign
Premalignant to SCC

A

Seborrheic keratoses

37
Q

Benign neoplasm of the extremity

Presents with blue, subungual discoloration associated with severe pain, point tenderness and cold sensitivity

A

Glomus tumor

38
Q

Most common site of common tumor

A

Hand

39
Q

Solitary soft tissue nodules on the legs or flank

Unencapsulated whorls of fibroblasts

A

Dermatofibroma

40
Q

Neural tumor that arises from the peripheral nerve sheath

Schwann cells packed in palisading rows

A

Neurilemmoma

41
Q

In situ Squamous cell CA is called

A

Bowen Disease

42
Q

In situ SCC specific to the penis is called

A

Erythroplasia of Queyrat

43
Q

Lesions arising from burn areas that can be a potential site for early metastasis of SCC

A

Marjolin ulcer

44
Q

High risk features of both SCC and BCC include lesions that are located in

A

Head and neck
Genitals
Mucosa

45
Q

Premalignant lesions of malignant melanoma include

A

Dysplastic nevus syndrome (BK mole)

Congenital nevi

46
Q

Appearance of mammary ridges or milk lines occur at what AOG

A

5-6 weeks

47
Q

Hypoplasia or complete absence of the breast
Costal cartilage and rib defects
Hypoplasia of the chest wall
Brachysyndactyly

A

Poland syndrome

48
Q

Normal nipple and areola but absent breast tissue is called

A

Amazia

49
Q

Provides structural support to the breast

A

Cooper suspensory ligament

50
Q

Hormone responsible for ductal development

A

Estrogen

51
Q

Hormone responsible for lobular development

A

Progesterone

52
Q

Gynecomastia is defined as enlargement of the male breast with the breast tissue measuring

A

2cm diameter

53
Q

Drugs with estrogenic activity

A

Diazepam
Ketoconazole
Cimetidine

54
Q

Bacteria responsible for epidemic puerperal mastitis

Transmitted via the suckling neonate

A

MRSA

55
Q

Variant of thrombophlebitis that involves the superficial veins of the anterior chest wall and breast

Benign, self limiting, resolves in 4-6 weeks

Tender firm CORD following distribution of the veins

A

Mondor disease

56
Q

Veins involved in Mondor disease

A

Hodor- Laging Taga Sagip

Lateral thoracic
Thoracoepigastric
Superficial epigastric

57
Q

Breast pathology that mimics cancer on examination, mammogram and gross pathologic exam

A

Sclerosing adenosis

58
Q

Baseline mammogram should be done at what age?

A

35 years

59
Q

BRCA mutation involved more in ovarian CA
Early onset, bilateral disease
Hormone receptor negative
90% lifetime risk for breast CA

A

BRCA 1

60
Q

BRCA 1 is found in what chromosome

A

Chr 17

61
Q

BRCA 2 is found in what chromosome

A

Chr 13

62
Q

BRCA mutation that has a 85% lifetime risk for breast CA

Well differentiated and express hormone receptors

A

BRCA 2

63
Q

Primary breast cancer that originates from the terminal duct lobular units

Occurs only in female breast
Marker of increased risk for invasive cancer

A

LCIS

64
Q

Primary breast cancer
Proliferation of the epithelium
True anatomic precursor of invasive carcinoma

Also called intraductal carcinoma

A

DCIS

65
Q

LCIS or DCIS

Bilateral
Multi centric

A

LCIS

66
Q

LCIS or DCIS

Mass, pain, discharge, microcalcifications

Ipsilateral

A

DCIS

67
Q

Chronic, eczematous, eruption of the nipple

Usually associated with DCIS and invasive cancer

(+) CEA

A

Paget disease

68
Q

(+) S-100

What CA?

A

Melanoma

69
Q

Pathognomonic histologic finding

Large, pale, vacuolated cells in the rete pegs of epithelium

A

Paget cells

70
Q

Most common type of invasive breast carcinoma

A

Invasive ductal

71
Q

Frequent phenotype among BRCA 1 cancers

A

Medullary carcinoma

72
Q

Invasive breast CA:
5th-6th decade
Solitary, firm mass with poorly defined margins
Central stellate configuration with chalky white or yellow streaks

A

Invasive ductal

Surgery (5 decks)

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