Skin and Cutaneous Disorders Flashcards
What antibiotic should be added to the typical serious cellulitis treatment regimen to treat organisms associated with necrotizing fasciitis?
Clindamycin
What syndrome can cause recurrent viral-like illnesses and aphthous ulcers in children?
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome
Impetigo treatment is MRSA is suspected
Bactrim
Impetigo treatment if systemic
Dicloxacillin, Cephalexin
Impetigo treatment if topical
Mupirocin, Retapamulin
What post-infectious sequelae are associated with impetigo?
Rheumatic fever and poststreptococcal glomerulonephritis (in GAS-associated impetigo)
Intermittent, colicky abdominal pain in a patient with HSP is suggestive of what intra-abdominal process?
Intussusception
Small vessel vasculitis with IgA deposits in skin or kidney;
dx?
HSP
What acquired immunodeficiency syndrome-defining illness resembles molluscum contagiosum with widespread centrally umbilicated skin lesions?
Disseminated cryptococcus
What should be a consideration in recurrent fungal infections?
Diabetes alters the urogenital flora making fungal infections more common and can be screened with historical information of polyuria or point of care testing with a finger-stick blood test for glucose.
What is the typical appearance of squamous cell carcinoma?
Irregular growth with erythema, induration, inflammation, crusting, or oozing
Antibiotic of choice for mild erysipelas
Penicillin
Up to how long after discontinuation of a suspected agent can Stevens-Johnson syndrome occur?
4 weeks
Flu like prodrome, urethritis, rash;
dx?
SJS
What is the treatment of choice for tinea versicolor?
Topical antifungals (e.g., terbinafine, azole antifungals)
Tx mycobacterium marinum
Clarithromycin
Minocycline or doxycycline
Bactrim
What is a life-threatening infection of the perineum that can begin as a cellulitis?
Fournier’s gangrene is a rapidly progressing infection of the skin, fat, fascia, or muscle that requires immediate surgical consultation to prevent further spread.
Cause of staph scalded skin syndrome
exotoxin producing Staph aureus
(+) Nikolsy bc sloughs
spares mucous membranes
Tx for staph scalded skin syndrome
Nafcillin or oxacillin
Supportive care
What sexually transmitted infection has been associated with erythema nodosum?
Chlamydia
First line treatment for erythema nodosum
NSAIDs
How does pemphigus vulgaris differ from bullous pemphigoid in presentation?
Patients with pemphigus vulgaris are often younger with painful, flaccid bullae which may involve the mucous membranes and are Nikolsky sign positive
Tx for widespread bullous pemphigoid
Prednisone
Common causes of allergic dermatitis
Poison ivy (uroshiol)
Nickel
Cobalt
Potassium dichromate
Tx of choice for scabies
Permethrin cream
Oral ivermectin for nursing home outbreaks
Linear burrow is pathognomonic for
Scabies
Treatment for pinworms
Mebendazole
Cellulitis treatment if PCN allergic
Clindamycin
Erythromycin
Azithromycin
Cellulitis tx if MRSA
Bactrim
Doxy
Clinda
Simple cellulitis tx
Cephalexin
Amoxicillin
Dicloxacillin
What antibiotic should be added to the typical serious cellulitis treatment regimen to treat organisms associated with necrotizing fasciitis?
Clindamycin
Treatment of oral candidiasis
Oral nystatin
What post-infectious sequelae are associated with impetigo?
Rheumatic fever and poststreptoccocal glomerulonephritis
A skin or kidney biopsy with IgA deposition confirms the diagnosis of:
Henoch-Schonlein purpura
Heme positive stool, +/- intussusception
Microscopic hematuria, +/- proteinuria
Periarticular disease of knees and ankles
dx?
HSP
Most common cause of jock itch (tinea cruris)
Trichophyton rubrum
Treatment options for moderate/systemic erysipelas
Ceftriaxone
Cefazolin
Treatment options for mild erysipelas
Amoxicillin
Cephalexin
Most common organism involved in erysipelas
beta-hemolytic strep (strep pyogenes)
Drugs that can cause SJS
Sulfa
Phenobarbitol. carbamezeine, lamotrigine
Allopurinol
NSAIDs
Infection that can cause SJS
Mycoplasma pneumonia
Flu-like prodrome;
Urethritis;
Lesions–mucosal and cutaneous;
Dx?
SJS
How long after discontinuation of a suspected substance can SJS occur?
Four weeks
Treatment for sporotrichosis
Itraconazole
Ampho B if severe, disseminated
Well demarcated granuloma w/ swelling;
lymphadenopathy;
works at aquarium;
dx?
Mycobacterium marinum
Treatment of mycobacterium marinum
Clarithromycin
Minocycline or doxycycline
Bactrim
What is a life-threatening infection of the perineum that can begin as a cellulitis?
Fournier’s gangrene
Immediate surgical consultation required
Nikolsky sign in Staph scalded skin syndrome
Positive
Nikolsky sign in SJS (and TEN)
Positive
