skin Flashcards
Hyperkeratosis
can be seen on biopsy
thickening of the stratum corneum
qualitative abnormality of the skin
seen in radiation damage to the skin (ie removing plantar warts)
Parakeratosis
keratinization with retained nuclei of the stratum corneum
normal on mucus membranes
Hypergranulosis
hyperplasia of the stratum granulosum
usually due to rubbing
Acanthosis
diffuse epidermal hyperplasia
due to chronic irritation/ inflammation
seen on path report
papillomatosis
surface elevation caused by hyperplasis and elargement of contiguous dermal papilla
-raised up compared to acanthosis
Onycholysis
separation of nail bed from the nail plate
From injury or fungal infections
Excoriation (abrasion or scratch)
Traumatic lesion breaking the epidermis
Raw linear area/deep scratch
Acantholysis
(pemphigus vulgaris)
loss of intercellular cohesion between keratinocytes
no desmosomes
can see the separation
spongiosis
intracellular edema of the epidermis
hydrophic swelling (balloning)
intracellular edema of keratinocytes
seen in viral infections
Exocytosis
infiltration of the epidermis by inflammatory cells from the dermis
erosion
incomplete loss of the epidermis
no bleedin
ulceration
complete loss of the epidermis revealing the dermis
bleeding is present
vacuolization
formation of vaculoes within or adjacent to cells
as you get older you get more of this within cells that contain pigment and cause age spots
Lentiginous
linear pattern of melanocyte proliferation within epidermal basal layer
