Skin

Question 1

Skin manifestations of tuberus scleosis

Answer 1

1. angiofibroma/adenoma sebaceum-nose , nasolabial folds and cheeck
2. ask leaf macule-hypopigmented , trunk
3. shagreen patch-leathery, lumbosacral region
4. periungal fibromas/koenen tumor

Question 2

X linked icthyoses

Answer 2

Only males
Deficiecy in steroid sulfate
Large dark , tightly adherent
Sites: generalised, flexures encroached
Ass: corneal opacities , cryptorchidism

Question 3

Icthyosis vulgaris

Answer 3

AD
Deficiency in filagggrin
Both males and females
Small, branny , except on shins where large.
Pasted in centre with upturned edge.
Extensors of limbs, lower back.
Associated with- hyperlinear palms and soles, keratosis pilaris , atopic diathesis