skin Flashcards

1
Q

what occurs in the corneum layer?

A

dead cells highly packed with keratin, squamous where dead cells fall off

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2
Q

what happens in lucidum layer?

A

highly translucent layer, very thing

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3
Q

What happens in the granulosum layer?

A

release of cytoplasmic organelles, high lipid concentrated secretions
Cells loose nuclei and are turned into ketatinised squames of the next layer

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4
Q

What happens in the spinosum layer?

A

become polyhedral shaped, thick tufts of keratin

Langerhan cells

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5
Q

What layer are the langerhan cells found in?

A

striatum spinosum

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6
Q

What layer are merkel cells and melanocytes found in?

A

Striatum basale

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7
Q

What is found in the papillary layer of the dermis?

A

less dense connective tissue

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8
Q

What is found in reticular layer of the dermis ?

A

dense connective tissue

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9
Q

Where is the dermal plexus found?

A

base of the dermis

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10
Q

where does squamous cell carcinoma begin?`

A

Granulosum layer

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11
Q

Where does a malignant melanoma start?

A

From melanocytes in basal layer

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12
Q

What does HPV do to cause warts?

A

Increased amounts of keratin

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13
Q

What does thick skin not have? (glabrous)

A

non hairy, no sebaceous or apocrine glands

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14
Q

what secrete sebum into hair follicles?

A

sebaceous glands

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15
Q

what are found throughout the skin and secrete sweat onto surface of skin and via what?

A

eccrine sweat glands

errcine duct

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16
Q

apocrine ducts, where are they found?

A

axillary and groin regions

17
Q

What glands are associated with arrector pilli muscle?

A

found bellow sebaceous glands, therefore when they contract hairs stands up and sebum can be pushed up hair

18
Q

What has sympathetic innervation within the skin?

A

arrector pilli and eccrine glands

vessels- dilate etc when hot

19
Q

What do free nerve endings act as?

A

nocireceptors or thermoreceptors.
Others are associated with the shafts of hair follicles, - rapidly adapting mechanoreceptors, firing when the hairs are moved.
Merkel cells in the basal layer of the epithelium. The resulting Merkel cell-neurite complexes act as mechanoreceptors that respond to pressure.

20
Q

What are encapsulated nerve endings?

A

Mechanoreceptors

21
Q

where are merkel cells found?

A

basal layer of epidermis

22
Q

where are parcinians corpuscles found?

A

within the hypodermis

23
Q

where are messiners corouscles found?

A

tip of dermal papillae

24
Q

where are the ruffini bodies found?

A

dermis

25
Q

what does the merkle cell respond to?

A

sustained touch and pressure

26
Q

what does the pacinians corpuscle respond to?

A

deep pressure, rapid vibration and coarse touch

27
Q

what does the meissners corpuscle respond to?

A

texture, pressure and vibration

28
Q

what does the ruffini body respond to?

A

stretching and shearing