Skin Flashcards
A pt presents with lesions in the scalp and/or nails. What is this a tell tale sign for diagnosis?
Psoriasis
This disorder has typical oval plaques with well defined borders and silvery scales
Psoriasis
How long does it take for a completely whole new epidermis to be replaced?
25-45 days
If new epidermis is being created faster than the 25-45 day normal range, what could develop from the faster, un-mature epidermis?
Psoriasis
Epidermis, dermis & hypodermis
What is the integument system (skin)
outermost superficial region?
epidermis
superficial fascia?
Hypodermis
Deepest region?
Hypodermis
What are the distinctive cell types of the outermost superficial region?
Keratinocytes, melanocytes and langerhans’ cells
What are the layers of the outermost superficial region?
Stratum Corneum, Stratum granulosum, Stratum spinosum and Stratum basale (germinativum)
What are the layers of the outermost superficial region is waterproof and why?
Stratum granulosum and it is water proof due to housing the glycolipids from lamellated granules and keratohyaline granules.
What are the layers of the outermost superficial region is housing the mitotic stem cells and what % of them are new cells?
Stratum Basale. they house 25% of all new cells and they also house merkel cells and melanocytes.
What are the layers of the outermost superficial region full of pre keratin?
Startum Spinosum. The pre keratin is made in thick bundles of intermediate filaments
What are the cells found in the Stratum Spinosum?
Keratinocytes, desmosomes and langerhans’ cells
produce the fibrous protein keratin (main structural protein of skin, hair, nails)
Keratinocytes
produce the brown pigment melanin
Melanocytes
epidermal macrophages that help activate the immune system
Langerhans’ cells
function as touch receptors in association with sensory nerve endings
Merkel cells
Which layer of the outermost superficial region are found mainly in the soles of feet and the palm of hands?
Statum lucidum
which cells in the outermost superficial region undergo mitosis, which produce keratinocytes?
Basal cells in the Stratum basale (GERMinativum) layer
No matter how dark or light someone skin color is… we all have the same amount of these?
Melanocytes
What protects us from UV light?
Melanocytes
What can cause free radicals?
UVA
What type of light causes direct damage to DNA?
UVB
This cell have a threadlike cytoplasmia-filled extensions that are used in passing these granules to the keratinocyte?
Melanocytes
Prevents UVB radiation damage, protective against skin cancers
Melanin
What type of person would have zero Melanin?
One affected with albinism
This has a greater local concentration of melanin
Freckles and moles
what stimulates melanin production?
Sunlight
Type I –VI
Fitzpatrick phototyping scale