Skin Flashcards

1
Q

A pt presents with lesions in the scalp and/or nails. What is this a tell tale sign for diagnosis?

A

Psoriasis

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2
Q

This disorder has typical oval plaques with well defined borders and silvery scales

A

Psoriasis

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3
Q

How long does it take for a completely whole new epidermis to be replaced?

A

25-45 days

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4
Q

If new epidermis is being created faster than the 25-45 day normal range, what could develop from the faster, un-mature epidermis?

A

Psoriasis

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5
Q

Epidermis, dermis & hypodermis

A

What is the integument system (skin)

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6
Q

outermost superficial region?

A

epidermis

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7
Q

superficial fascia?

A

Hypodermis

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8
Q

Deepest region?

A

Hypodermis

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9
Q

What are the distinctive cell types of the outermost superficial region?

A

Keratinocytes, melanocytes and langerhans’ cells

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10
Q

What are the layers of the outermost superficial region?

A

Stratum Corneum, Stratum granulosum, Stratum spinosum and Stratum basale (germinativum)

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11
Q

What are the layers of the outermost superficial region is waterproof and why?

A

Stratum granulosum and it is water proof due to housing the glycolipids from lamellated granules and keratohyaline granules.

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12
Q

What are the layers of the outermost superficial region is housing the mitotic stem cells and what % of them are new cells?

A

Stratum Basale. they house 25% of all new cells and they also house merkel cells and melanocytes.

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13
Q

What are the layers of the outermost superficial region full of pre keratin?

A

Startum Spinosum. The pre keratin is made in thick bundles of intermediate filaments

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14
Q

What are the cells found in the Stratum Spinosum?

A

Keratinocytes, desmosomes and langerhans’ cells

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15
Q

produce the fibrous protein keratin (main structural protein of skin, hair, nails)

A

Keratinocytes

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16
Q

produce the brown pigment melanin

A

Melanocytes

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17
Q

epidermal macrophages that help activate the immune system

A

Langerhans’ cells

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18
Q

function as touch receptors in association with sensory nerve endings

A

Merkel cells

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19
Q

Which layer of the outermost superficial region are found mainly in the soles of feet and the palm of hands?

A

Statum lucidum

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20
Q

which cells in the outermost superficial region undergo mitosis, which produce keratinocytes?

A

Basal cells in the Stratum basale (GERMinativum) layer

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21
Q

No matter how dark or light someone skin color is… we all have the same amount of these?

A

Melanocytes

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22
Q

What protects us from UV light?

A

Melanocytes

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23
Q

What can cause free radicals?

A

UVA

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24
Q

What type of light causes direct damage to DNA?

A

UVB

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25
This cell have a threadlike cytoplasmia-filled extensions that are used in passing these granules to the keratinocyte?
Melanocytes
26
Prevents UVB radiation damage, protective against skin cancers
Melanin
27
What type of person would have zero Melanin?
One affected with albinism
28
This has a greater local concentration of melanin
Freckles and moles
29
what stimulates melanin production?
Sunlight
30
Type I –VI
Fitzpatrick phototyping scale
31
Type I is?
Very light/pale white which that person always burns, never tans
32
type VI is?
black very dark brown to black, never burns and can be very easily de-pigmented
33
skin region containing strong, flexible connective tissue
Dermis
34
Cell types include fibroblasts, macrophages, and occasionally mast cells and white blood cells
Dermis
35
Only this layer is vascularized?
Dermis
36
what are the two layers of the dermis?
Papillary and reticular
37
main structural protein of connective tissue
Collagen
38
protein, imparts elastic properties
Elastin
39
fine meshwork protein
Reticulin
40
the dermis contains what proteins?
Collagen, Elastin, and Reticulin
41
Papillary layer contains?
dermal papillae
42
cleavage or tension lines where less dense, important for surgical incisions – parallel incisions heal with less scar and faster
Reticular Layer
43
Extreme dermal stretch might result in?
striae
44
what are striae?
stretch marks
45
lines that surgeons will cut along?
Langerhans lines
46
Subcutaneous layer is called?
Hypodermis
47
Nails, hair, Sebaceous Glands, Eccrine Sweat Glands, Apocrine Sweat Glands, Blood Vessels Nerves and Fat
Dermal Appendages of the hypodermis
48
Hard Keratin
Nails
49
responsible for nail growth
Nail Matrix, Grow about 1mm every week
50
where does one check for capillary refill?
nails
51
fungal disease of the nail that is hard to treat
onychomycosis
52
nail angle increased to atleast 180 degrees is called?
clubbing
53
pitting of nails indicate?
psoriasis
54
What are the 4 types of burns?
Radiation Thermal Chemical Electrical
55
How do you determine how significant the burn damage is?
Depth and Size of the burn
56
Bulla | Blister
larger than .5cm | 2nd degree burn
57
pustule
Pus filled sac | Pimple
58
Cyst
Fluid filled mass deep
59
Telangiectasia
(Spider angioma) Tiny red blood vessel lesion formed by dialation of a group of blood vessels radiating from a central arteriole Most common on face neck or chest
60
Scale
Think flake of exfolative epidermis | Ex dandruff
61
Keloid
Abnorm growth of scartissue thick and irrgecular
62
Lichenification
Leathering and thickening | ex: in atopic dermatitis
63
Excoriation
Scratch mark
64
Macule
discolored flat spot up to 1 cm | Ex freckle
65
Fissure
Linear crack in the skin
66
Erosion
Gnawed away Loss of superficial epidermis leaving an area of moisture but no bleeding Ex: after vesicle rupture
67
Ulcer
Open soar on the skin Or mucus membrane Can bleed and scar; sometimes accompanied by infection Ex: decubitis ulcer
68
Petechiae
Reddish brown spot, small purpura | Hemmoragic spots, indicate bleeding
69
Purpura
Purple spot, from hemorrhages into the skin
70
Comedone
Open- open to skin surface with black center from melanin exposed to air Closed- below skin surface with white center
71
Patch
Flat discolored are on the skin larger than 1cm | Ex vitiligo
72
Papule
Solid mass on the skin up to .5cm in diameter | Ex Mole
73
Plaque
Solid mass greater than 1 cm in diameter | Limited to skin surface
74
Nodule
Solid mass greater than 1 cm | Extends deeper into epidermis
75
Tumor
Solid mass larger than 1-2cm
76
Wheal
Area of localized skin edema | Ex: hive
77
Vesicle
Little bladder Elevated fluid filled sac up to .5 cm Within or under epidermis Ex: blister