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Skin > Skin > Flashcards

Skin Flashcards

1
Q

Give 6 functions of skin?

A

1) Barrier to infection
2) Thermoregulation
3) Protection against trauma
4) Protection against UV
5) Vitamin D synthesis
6) Regulation of H2O loss

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2
Q

State 3 layers of skin? (out to in)

A

1) Epidermis
2) Dermis
3) Subcutaneous tissue

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3
Q

What are layers of epidermis?

A

1) Corneum
2) Lucidum
3) Granulosum
4) Spinosum
5) Basale

Come lets get sunburned

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4
Q

Label dermis layers (R)?

A
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5
Q

What is dermis composed of?

A

Glands
Tough connective tissue

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6
Q

What is subcutaneous tissue composed of?

A

Fat and connective tissue

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7
Q

What links corneocytes?

A

Corneodesmosomes

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8
Q

What cells contain NMF?

A

Corneocytes

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9
Q

What structures surronds corneocytes?

A

Cornified envelope

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10
Q

What is NMF and pH?

A

Natural moisturising factor
Maintain pH

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11
Q

Function of lipid lamellae?

A

Water barrier
Allow cells to swell

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12
Q

What structure allows cells to swell?

A

Lipid lamellae

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13
Q

Label

A
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14
Q

What is pH of skin?

A

4.7
Below 5

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15
Q

Function emolients?

A

Trap moisture in skin

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16
Q

Function humectants?

A

Trap moisture
Maintain low pH

17
Q

What does profilaggrin turn into? (pathway)

A

1) Profilaggrin
2) Filaggrin
3) NMF
4) Maintain low pH

18
Q

What is process of shedding cells from surface called?

A

Desquamation

19
Q

Why does skin have low pH?

A

Moisture in
Bacteria out

20
Q

Explain process of desquamation?

A

1) Degradatory proteases
2) Corneodesmosomes
3) Desquamation

Low pH inhibits protease inhibitors

21
Q
A
22
Q

State process of acne?

A

1) Hypercornification of skin
2) Blocks hair follicle entrance
3) Sebum released from sebaceous glands
4) Trapped in narrow hair follicle
5) No oxygen provides anaerobic conditions
6) Allows propionic bacteria to multiply
7) Bacteria breakdown triglycerides into fatty acids
8) Result: Increased irritation
Increased inflammation
Attraction of neutrophils
9) Pus and further inflammation

23
Q

What process blocks hair follicle entrance?

A

Hypercornification

24
Q

What is released from sebaceous glands?

A

Sebum

25
Q

What bacteria form acne?
Function?

A

Propionic bacteria
Breakdwon triglycerides into FA

26
Q

What does breakdown of triglycerides into FA cause?

A

Increased irritation
Increased inflammation
Attraction of neutrophils
This leads to pus and further inflammation

27
Q

What gives skin colour?

A

Melanocytes
Release melanin

Skin (1 decks)

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