Skin Flashcards
How does the skin maintain a constant body temp?
1) insulating fat and hair 2)accelerating heat loss w/ sweat production/dense microvasculature
What are the 4 phases of cutaneous wound repair?
coagulation, inflammatory, proliferative migratory, remodeling
Bullous pemphigoid blisters present as tense bullae where?
between the epidermis and dermis
What is the dysfunction associated with psoriasis?
rate of epidermal turnover is increased leading to thickening=>differentiation is limited due to decrease in time
What is the most common presentation of basal cell carcinoma?
pearly, erythematous papules/plaques w/ rolled borders and telangectasias in sun exposed areas
What cell plays a prominent role in allergic contact dermatitis?
langerhans cells
What type of hypersensitivity rxns are langerhans cells associated with?
Type IV
What are the 2 layers of the dermis?
papillary and reticular dermis
What is the pathophys of a keloid?
result of uncontrolled synthesis and excessive collagen deposition at prior dermal injury sites and wound repair
What is the major effector cell of urticaria? where is is located?
mast cell => dermis
What type of hypersensitivity rxn is associated with mast cells?
type I
What is a disorder of the subcutis that appears as deep seeded erythematous nodules typically on shins?
erythema nodosum
What type of disease is erythema nodosum?
inflammation of the subcutis
Acne vulgaris is a disorder of what?
pilosebaceous unit
What 4 factors are associated with acne vulgaris?
1) plugging of hair follicle (abnormal keratinization=>comedones) 2) P. acnes in follicle; 3) androgen hormones; 4) increased sebaceous gland activity
