Skin Flashcards
What is the risk of PNI, LN, DM for BCC
very low
What is the risk of PNI, LN, DM for SCC
PNI is 2-15%
Well diff SCC LN+ 1%
Risk factors for greater LN+ for SCC
>3 cm
>4 mm depth
Lips
Temporal lesions
SCC from burn scars or osteomyelitis
What syndrome increases risk of BCC and medulloblastoma
Gorlin syndrome
What is etiology of Merkel cell
Merkel polyoma virus
What imaging is needed for Merkel cell
PET CT
When should MRI be ordered for skin cancers
Concern for PNI
T1 SCC/BCC
<2 cm
T2 skin
2-4 cm
T3 skin
>4 cm and/or
PNI and/or
Deep invasion or minor bone erosion
T4a skin
cortical bone or marrow invasion
T4b skin
BOS or foramen involvement
What is preferred managment of BCC or SCC
Moh’s surgery
What are the indications for post-op RT for SCC or BCC
- Positive margin
- Extensive PNI or large nerve involvement
- Skeletal muscle, bone/cartilage invasion or other high risk features
What is large nerve involvement for skin cancer
>0.1 mm
What are indicates for RT to nodes for SCC/BCC
N+ disease or ECE
What levels are treated for skin cancers
IB to III
Which skin lesions should be offered definitive RT
Central lesions > 5 mm
eyelids, tip of nose, lip commissure
Large lesions with poor comesis after Moh’s
If incurable skin cancer, what is another treatment option
cemiplimab
PD1 inhibitor
What is the preferred RT approach for SCC/BCC
Electron beam therapy