Skills test! Flashcards
what therapeutic class is glycopyrrolate
Antipasmodics (suppresses muscle spasm)
what pharmacological class is glycopyrrolate
anticholinergics (blocks acetylcholine NT’s - inhibit parasympathetic nerve impulse)
what is the indications for glycopyrrolate
inhibits salivation & excess respiratory secretions when given preoperatively or for palliative care.
(Reverses some of the secretory & vagal actions of cholinesterase inhibitors used to treat non depolarizing neuromuscular blockade) (Adjunctive management peptic ulcer disease)
What is the action of gylcopyrrolate
Inhibits the action of acetylcholine @ postganglionic sites located in smooth muscle, salt. glands & CNS. Low doses decrease sweating, salivation & respiratory secretions. Intermediate doses increase HR & large doses decrease GI & GU motility.
what is the therapeutic effect of glycopyrrolate
Decreased GI & resp secretions. Not well absorbed orally. Crosses placenta
Onset of glycopyrrolate
15-30 minutes or longer
peak of glycopyrrolate
30-45 minutes or longer
duration of glycopyrrolate
2-7 hours
half life of glycopyrolate
~2 hours
when is glycopyrolate contraindicated
hypersensitivity, glaucoma, hemorrhage, tachycardia, ulcerative colitis, toxic megacolong
what are side effects of glycopyrollate
headache, congestion, tachycardia, dry mouth, vomiting, urinary hesitancy, flushing
interactions of glycopyrollate
increased GI mucosal lesions with oral potassium chloride, may alter absorption of oral drugs by slowing motility
what to assess before giving glycopyrolate
HR, BP, RR, Intake/output in geriatric, bowel sounds, LBM, may cause decreased uric acid
what is the antidote for glycopyrolate
Neostigmine
What should you teach the patient
will decrease respiratory secretions. Avoid extreme temperatures, may cause dizziness, notify if eye pain.
what is the T class of dimenhydrinate
Antiemetics, antihistamines
what is the indication for dimenhydrinate
N/V, Dizzy, vertigo w/ motion sickness
what is the action of dimenhydrinate
Inhibits vestibular stimulation, significant CNS depression, anticholinergics, antihistaminic, antiemetic
what is the therepeatuci effect of Dimenhydrinate
decrease vestibular stimulation - prevent motion sickness