Sketchymicro viral images/medical symptoms: DNA viruses Flashcards

erythema multiforme: HSV-1/2

herpetic witlow HSV1/2

Gingivastomatitis, hsv 1/2

keratoconjunctivitis, hsv 1/2

keratoconjunctivitis, hsv 1/2

gingivastomatitis, hsv 1,2

herpes labialis, hsv 1/2
which hsv causes genital herpes?
hsv 2

African Burkitt Lymphoma: large jaw swelling/lymphadenopathy

Burkitt lymphoma, jaw swelling/lesion
how would you distinguish this from candidiasis?

this will likely scape off if it is oral hairy leukoplakia seen in EBV infections;
in whom is this lesion pattern most likely found?

hiv patients: oral hairy leukoplakia indicating EBV infection. benign lesion, not a cancerous precursor lesion.

cervical lymphadenopathy seen with mononucleosis
first thought

mononucleosis (EBV) caused submandibular lymphadenopathy

non-specific, but can EBV-pharyngitis
Child was diagnosed with strep pharyngitis and given a medication. The image was taken several hours later. What was the medication and what is a possible diagnosis?

maculopapulary rash: Nonspecific allergic rxn but according to sketchy micro this is a typical presentation when EBV is misdiagnosed
nasopharyngeal carcinoma
EBV is the most common cause; asian men have the highest incidence rate

CMV esophagitis

HSV 1 esophagitis

“blue berry muffin rash” can seen with cytomegalovirus (CMV), rubella, and parvovirus B19

“pizza pie retinitis” or CMV retinitis
How would you single out the identity of the virus associated with this MRI

paraventricular calcifications: CMV
Calcifications may occur in the following conditions:
- Viral infections such as:
- Rubella: in the USA, only 10% of females are susceptible
- Varicella-zoster: only 15% of females are susceptible
- Herpes Simplex infection
- Venezuelan Equine Encephalitis
- Toxoplasmosis
- Congenital Cytomegalovirus infection: most common congenitally acquired infection
- Infarctions
- Teratoma
- Familial mitochondrial encephalopathy
- 3-hydroxyisobutyric aciduria
- Moebius syndrome
- Fahr”s syndrome
Most of these diagnoses can readily be eliminated since they do not present with periventricular calcifications but instead basal ganglia or parenchymal calcifications. The only serious differential diagnosis is the Familial mitochondrial encephalopathy. The ultrasound findings of intracranial calcifications are mostly important to distinguish between CMV and Toxoplasmosis. CMV most commonly is represented in the periventricular area as compared to Toxoplasmosis where the lesions are seen more commonly in the brain parenchyma.
<big>Diagnosis: Congenital CMV</big>
Temporal lobe distinguished in this image, what virus most likely localizes to the temporal lobe in order to cause an encephalitis?

herpetic temporal lobe encephalitis
EBV vs CMV: Hepatosplenomegaly or Splenomegaly
EBV most likely splenomegaly; CMV more likely hepatosplenomegaly
symptoms of congenital CMV
blue berry muffin rash, jaundice, hepatosplenomegaly, sensorineural hearing loss, ventriculomegaly, periventricular calcifications, seizures
Congenital Varicella Zoster syndrome
- Limb hypoplasia
- scarring in a dermatomal pattern
- microcephaly
- optic atrophy
- choriorentisis
- coritcal atrophy
- seizures
- cataracts
- renal hydrodysgenesis

herpes zoster opthalmicus: V1 is infected
Likely diagnosis and what makes its distinct

rash in a dermatomal pattern, but it crosses the midline: indicating this is likely herpes zoster in an immunocompromised patient

Varicella Zoster: chicken pox. Generalized exanthema.

varicella zoster, generalized exanthemas (chicken pox)

herpes zoster (shingles). varicella zoster is called herpes zoster once it is reactivated.
child has a fever lasting 3-4 days and develops a rash on the 4th day. shown in the image is the rash (rash is sparing the face). what was one of the doctor’s fears during the febrile period?

seizures.
this is HHV-6: roseola, rose-6-eola