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M&M Histology > Skeletal muscles Histology > Flashcards

Skeletal muscles Histology Flashcards

1
Q

Sites of skeletal muscles ?

A

All muscles attached to the skeleton
Tongue muscles
Eye muscles
Pharynx and larynx

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2
Q

What’s the name of cell membrane of muscle fibres

A

Sarcolemma

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3
Q

What’s the name of cytoplasm in muscle fibres

A

Sarcoplasm

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4
Q

Characters of muscle fibres

A

Voluntary
Striated
Don’t branch

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5
Q

What’s the name of the connective-tissue surrounding the whole muscle

A

Epimysium (EP)

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6
Q

Skeletal muscle bundles called

A

Fascicles

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7
Q

Skeletal muscles bundles (Fascicles) are separated by dense connective tissue called

A

Perimysium (P)

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8
Q

Each muscle fiber enclosed by loose connective tissue called

A

Endomysium (En)

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9
Q

When you look at a skeletal muscle with a light microscope what are the things that you comment on ?

A 
Number of cells
Branching
Length
Diameter
Nucleus
Cytoplasm
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10
Q

When you look to a skeletal muscle with a light microscope what do you see ?

A

‏ Single elongated cell
No branching
Lengt 1-40 mm
Diameter 10-100 um

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11
Q

Nucleus of skeletal muscles ?

A

Multinucleated
Flattened
Peripheral

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12
Q

Sarcoplasm (Cytoplasm of skeletal muscles) characters?

A 
Acidophilic
Regular striation (myofibrils)
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13
Q

When you look at a skeletal muscle with an electron microscope what are the things that you comment on ?

A 
Cytoplasmic content 
Myofibrils 
Sarcomeres 
Thin and thick filaments 
Conducting system
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14
Q

Cytoplasmic content of skeletal muscles ?

A 
Sarcoplasmic reticulum 
Numerous mitochondria
Myoglobin
Beta glycogen granules 
Myofibrils
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15
Q

Myofibrils of skeletal muscles characters ?

A

Longitudinal contractile elements

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16
Q

Myofibrils bands ?

A 
Light band (I-band) : thin filaments only
Dark band (A-band) : thin and thick filaments
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17
Q

H-zone of myofibrils ?

A

Light area in the center of A-band

18
Q

Z-line of myofibrils ?

A

Dark line in the center of I-band

19
Q

What does z-line consist of ?

A

Alpha-actinin protein which ties adjecent sarcomeres

20
Q

Myofibrils consist of successive …………….

A

Sarcomeres

21
Q

The beginning and the end of the sarcomeres ?

A

From Z-line to Z-line

22
Q

A Sarcomere consists of ?

A

A-band (center) (thin and thick filaments)

1/2 I-band (each side) (think filaments)

23
Q

Protein content of thin filaments ?

A

Actin
Tropomyosin
Troponin complex

24
Q

Thick filaments protein content ?

A

Myosin

25
Q

F-actin molecule component ?

A

Formed of 2 strands of G Actin molecules twisted in a double helix

26
Q

G-actin molecules has ?

A

Binding site for myosin

27
Q

Tropomyosin components and site ?

A

Long thin molecule formed of 2 polypeptide chains

Site : between actin strands

28
Q

Troponin complex parts ?

A

TnT
TnC
TnI

29
Q

Troponin parts function :

A

T : bind to tropomyosin
C : binds to calcium ion
I : inhibits Actin-myosin interaction

30
Q

Each tropomyosin spans …………….

A

7 G-actin

1 troponin complex

31
Q

Myosin filaments parts ?

A

Head

Tail

32
Q

Head of myosin ?

A

Formed of two identical heavy chains

Has ATP-binding site
Has actin binding site

33
Q

Tail of myosin ?

A

Formed of 2 light chains

Bounded to the heavy chains

34
Q

Skeletal muscles conducting system triad :

A

1 T-tubule

2 sarcoplasmic tubules

35
Q

T-tubule site :

A

At A-I junction

36
Q

Classifications of muscle fibres according to concentration of myoglobin in relation to fiber diameter

A 
Type I (red, slow) fibers
Type II (white, rapid) fibers
Intermediate fibers
37
Q

In the histochemical staining of mitochondria, the muscle fibres looks

A

Type I : dark

Type II : light

38
Q

In the histochemical staining of myosin ATPase activity is the muscles fibres looks :

A

Type I : pale

Type II : dark

39
Q

What are the changes that occur in the myoneural junction :

A

The nerve replaces myelin with Shawn cells

The axoplasm contains numerous
Mitochondria
Synaptic vesicles

The sarcolemma (muscle cell membrane) forms numerous junctional folds has ACh receptors.

40
Q

Synaptic cleft ?

A

Space between the axon and muscle

M&M Histology (1 decks)

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