Skeletal Muscle Physiology Flashcards

1
Q

What is muscle?

A

Specialized tissue that can contract and turn energy into motion

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2
Q

Functional divisions of muscle

A

Voluntary and involuntary

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3
Q

Structural divisions of muscle

A

Striated and smooth

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4
Q

Property of skeletal muscle

A

Striated voluntary

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5
Q

Property of smooth muscle

A

Smooth involuntary

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6
Q

Property of cardiac muscle

A

Striated involuntary

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7
Q

Location of skeletal muscle

A

Most abundant tissues, attached to skeleton bones

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8
Q

Location of smooth muscle

A

BVs, digestive sys, bladder

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9
Q

Location of cardiac muscle

A

Walls of heart

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10
Q

Function of skeletal muscle

A

Move and support skeleton

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11
Q

Function of smooth muscle

A

Controls slow and involuntary movements

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12
Q

Function of cardiac muscle

A

Contraction of atria and heart ventricles, as well as blood circulation throughout the body

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13
Q

How is skeletal muscle attached to bone?

A

Tendons

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14
Q

What is a tendon?

A

Bundle of collagen fibres

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15
Q

What is skeletal muscle made up of

A

Thousands of muscle fibres wrapped in connective tissue sheaths. Very long, cylindrical, multinucleate

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16
Q

How are muscle fibres formed

A

During development, myoblasts fuse with eachother to make myotubes

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17
Q

What are myofibres composed of

A

Myofibres (muscle fibres) are composed of myofibrils, which are made of up filaments/myofilaments that contain actin and myosin

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18
Q

Bending pattern

A

In skeletal muscle, have this when looked at under microscope because of filament arrangement in muscle fibres

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19
Q

Endomysium

A

Connective tissue layer surrounding a fiber

20
Q

Fascicle

A

Group of indiv muscle fibres

21
Q

Perimysum

A

Connective tissue layer surrounding a fascicle

22
Q

Epimysium

A

Connective tissue sheath surrounding the muscle

23
Q

Tendon

A

Connective tissue layers at the ends of the muscle that attach the muscle to the skeleton at a myotendinous junction

24
Q

What is a myotendinous junction?

A

A specialized location at muscle-tendon interface that acts as primary site of force transmission

25
Q

What are tendon and connective tissue composed of? Why?

A

Elastin and collagen—contribute to passive muscle tension and prevent damage to muscle fibres as they stretch

26
Q

Sarcolemma

A

Cell membrane of muscle fibres

27
Q

Sarcoplasma

A

Cytoplasm of muscle fibres

28
Q

Sarcoplasmic reticulum

A

Channels through sarcoplasma

29
Q

Transverse tubule network

A

Formed by invaginations of sarcoplasma deep in muscle fibres. Network carries depolarization from APs from muscle surface to muscle interior

30
Q

What are myofibres composed of

A

100s to 1000s of myofibrils

31
Q

What are myofibrils made of

A

Myofilaments

32
Q

Thick myofilaments

A

Made of myosin, 16nm

33
Q

Thin myofilaments

A

Made of actin, 6nm

34
Q

Banding pattern

A

Myosin and acting arranged in repeating units: A-bands and I-bands

35
Q

A-bands

A

Dark, contain myosin and actin filaments, H-zone and M-line

36
Q

I-bands

A

Light, only actin filaments, Z-line

37
Q

Area between 2 Z-lines is called…

A

Sarcomere

38
Q

What is a sarcomere?

A

Basic contractile unit of muscle fibres

39
Q

What is a sarcomere?

A

Basic contractile unit of muscle fibres, responsible for striated appearance of muscles

40
Q

Bands of sarcomeres

A

A-band in center, half an I-band on either side

41
Q

A-bands in EM

A

Dark, thick and thin filaments overlap

42
Q

I-bands in EM

A

Light, only thin filaments

43
Q

I-band in intense microscope

A

More dark striations (Z-line)

44
Q

A-band in intense microscope

A

Additional dark striations (M-line) and light stripes (H-band)

45
Q

H-band

A

AKA bare zone. No myosin head, no overlap of thick and thin filaments. Also means there is no overlap in I-band either

46
Q

Each thick filament is surrounded by:

A

6 thin filaments

47
Q

Each thin filament recieves:

A

Cross-bridge attachments from 3 thick filaments