Skeletal Muscle Physiology Flashcards

1
Q

What is muscle?

A

Specialized tissue that can contract and turn energy into motion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Functional divisions of muscle

A

Voluntary and involuntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Structural divisions of muscle

A

Striated and smooth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Property of skeletal muscle

A

Striated voluntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Property of smooth muscle

A

Smooth involuntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Property of cardiac muscle

A

Striated involuntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Location of skeletal muscle

A

Most abundant tissues, attached to skeleton bones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Location of smooth muscle

A

BVs, digestive sys, bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Location of cardiac muscle

A

Walls of heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Function of skeletal muscle

A

Move and support skeleton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Function of smooth muscle

A

Controls slow and involuntary movements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Function of cardiac muscle

A

Contraction of atria and heart ventricles, as well as blood circulation throughout the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How is skeletal muscle attached to bone?

A

Tendons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is a tendon?

A

Bundle of collagen fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is skeletal muscle made up of

A

Thousands of muscle fibres wrapped in connective tissue sheaths. Very long, cylindrical, multinucleate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How are muscle fibres formed

A

During development, myoblasts fuse with eachother to make myotubes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are myofibres composed of

A

Myofibres (muscle fibres) are composed of myofibrils, which are made of up filaments/myofilaments that contain actin and myosin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Bending pattern

A

In skeletal muscle, have this when looked at under microscope because of filament arrangement in muscle fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Endomysium

A

Connective tissue layer surrounding a fiber

20
Q

Fascicle

A

Group of indiv muscle fibres

21
Q

Perimysum

A

Connective tissue layer surrounding a fascicle

22
Q

Epimysium

A

Connective tissue sheath surrounding the muscle

23
Q

Tendon

A

Connective tissue layers at the ends of the muscle that attach the muscle to the skeleton at a myotendinous junction

24
Q

What is a myotendinous junction?

A

A specialized location at muscle-tendon interface that acts as primary site of force transmission

25
What are tendon and connective tissue composed of? Why?
Elastin and collagen—contribute to passive muscle tension and prevent damage to muscle fibres as they stretch
26
Sarcolemma
Cell membrane of muscle fibres
27
Sarcoplasma
Cytoplasm of muscle fibres
28
Sarcoplasmic reticulum
Channels through sarcoplasma
29
Transverse tubule network
Formed by invaginations of sarcoplasma deep in muscle fibres. Network carries depolarization from APs from muscle surface to muscle interior
30
What are myofibres composed of
100s to 1000s of myofibrils
31
What are myofibrils made of
Myofilaments
32
Thick myofilaments
Made of myosin, 16nm
33
Thin myofilaments
Made of actin, 6nm
34
Banding pattern
Myosin and acting arranged in repeating units: A-bands and I-bands
35
A-bands
Dark, contain myosin and actin filaments, H-zone and M-line
36
I-bands
Light, only actin filaments, Z-line
37
Area between 2 Z-lines is called…
Sarcomere
38
What is a sarcomere?
Basic contractile unit of muscle fibres
39
What is a sarcomere?
Basic contractile unit of muscle fibres, responsible for striated appearance of muscles
40
Bands of sarcomeres
A-band in center, half an I-band on either side
41
A-bands in EM
Dark, thick and thin filaments overlap
42
I-bands in EM
Light, only thin filaments
43
I-band in intense microscope
More dark striations (Z-line)
44
A-band in intense microscope
Additional dark striations (M-line) and light stripes (H-band)
45
H-band
AKA bare zone. No myosin head, no overlap of thick and thin filaments. Also means there is no overlap in I-band either
46
Each thick filament is surrounded by:
6 thin filaments
47
Each thin filament recieves:
Cross-bridge attachments from 3 thick filaments