Skeletal Muscle 3 Flashcards

1
Q

What is an isometric contraction?

A

No muscle shortening, the load exceeds the tension created. Load weight force= force developed by muscle

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2
Q

What is an isotonic contraction? What are the two kinds?

A

Movement of the muscle, where there is a mismatch of load and tension.
Concentric and eccentric.

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3
Q

What is a concentric contraction?

A

Muscle shortening, where load weight force

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4
Q

What is eccentric contraction?

A

Muscle lengthening, load weight force > muscle force

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5
Q

What can eccentric contractions cause?

A

DOMS (delayed onset muscle soreness)

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6
Q

What is the current hypothesis on training?

A

That eccentric contraction will potentially make more sarcomeres in series with each other, so can operate at shorter lengths.

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7
Q

What is the length tension relationship?

A

That sarcomeres can create the most tension (force) at an optimal length (2.1/2.2 microns). Shortening this length will rapidly decrease the tension, and lengthening less so.

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8
Q

In terms of force and velocity, what happens during an isotonic contraction?

A

as the velocity increases, the force of contraction decreases, then as it decreases, force increases.

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9
Q

When is contraction most efficient?

A

1/3 of the maximum rate of shortening

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10
Q

How does creatine produce ATP?

A

creatine phosphate + ADP —( creatine kinase)—> creatine + ATP

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11
Q

What are type one muscle fibres?

A

Slow oxidative fibres:

  • red in colour (myoglobin)
  • high mitochondria
  • present in postural muscles/ endurance atheletes
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12
Q

What are type 2a fibres?

A

Fast oxidative fibres:

  • red in colour (myoglobin)
  • oxidative and glycolytic metabolism
  • high mitochondria count
  • prone to fatigue
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13
Q

What are type 2b fibres?

A

Fast glycolytic fibres:

  • white
  • anaerobic metabolism
  • good for short fast bursts
  • resistance training –> type 2a
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14
Q

What is central muscle fatigue??

A

decreased CNS activation and/or decreased motor units recruited

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15
Q

What is peripheral muscle fatigue?

A

Decreased ca2+ sensitivity, slower x bridge formation

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16
Q

What can peripheral muscle fatigue cause?

A

metabolite accumulation; depletion of energy supplies (glycogen)

17
Q

What is the accumulation theory?

A

That an increase in ROS; K+; NH3; Pi and lactic acid all contribute to a decrease in the force of muscle contraction

18
Q

What causes DMD?

A

A mutation of the gene which codes for dystrophin. ( anchors elements of the myocyte to cytoskeleton)

19
Q

What is sarcopenia?

A

Muscle atrophy as a consequence of age.

20
Q

In sarcopenia, what is happening with the muscle fibre types?

A

Denervation of type 2 fibres is occurring and there is an increase of type 1 fibres.