skeletal muscle Flashcards
How is the movement of a joint accomplished?
Internal forces initiated by muscle fibers are transmitted across connective tissue to the tendon causing the movement of the skeleton
Epimysium
outermost layer of connective tissue covering the muscle
Endomysium
connective tissue covering each muscle fiber cell
sarcolemma
has junctional folds in the innervation zone where action potentials are transmitted
transverse tubules
extend laterally through fiber to allow impulses to reach all myofibrils
Sarcoplasmic reticulum
tubules paralleling myofilaments; store Ca+ which is essential for control of contraction
myofibrils
fine protein filaments that contain contractile elements
Sarcomere
the smallest functional unit of a muscle
Myosin (thick) filament
contains 2 protein strands that form globular heads that attach to actin
actin ( thin) filament
composed of mostly actin but tropomyosin and troponin as well
what proteins are responsible for cross-bridging?
actin and myosin
What’s in the I-band?
thin filamments only
What’s in the A-band?
thin and thick filaments
What’s in the H-band?
thick filaments
what is the excitation component of excitation-contraction coupling?
electrical impulse initiated by a motor neuron propagates to fibers and initiates contraction
what happens when an electrical signal is transmitted?
It transferred to a chemical signal of neuromuscular function
what happens in excitation-contraction coupling?
- When ACh is received by the receptors, action potential is transmitted to the muscle
- The action potential then goes down the T-tubules and causes the release of calcium to be released into the sarcoplasm
- The calcium ions then bind to troponin which moves the tropomyosin
why do muscle fibers shorten?
the cross Bridging occurs when the myosin heads detaches, tilt its head, and reattaches
what is power stroke?
the tilting of myosin head from 90 degrees to 45 degrees
what is the sliding filament theory?
the repeated actions of the attachment of the myosin head and the power stroking
how does cross-bridging relate to force?
the more cross-bridging cycling happens, the more force is generated. Larger muscles have alot more sarcomeres making more cross-bridging cycles.
what is needed for the sliding filament theory?
ATP is needed for the sliding filament theory. it binds to myosin during myosin-actin attachment.
Type I muscle fibers
- slow twitch
- slow oxidative
- contractile speed = slow
- fatigue resistance = high
- motor unit strength = low
Type II muscle fibers
- fast twitch
- oxidative compacity = low
- contractile speed = fast
- fatigue resistance = low
- motor unit strength = high
Why do type II muscle fibers have a faster twitch?
Type 2 has a faster twitch because APase works more creating faster contractions, and a more developed SR causing Ca+ delivery to be enhanced