Sjogren's syndrome Flashcards
1
Q
what is Sjogrens syndrome?
A
chronic autoimmune inflammatory disorder
characterised by diminished lacrimal and salivary gland secretion
primary form is not associated with any other disease, but secondary for is associated with another underlying rheumatic disease
2
Q
what are the common symptoms and signs of Sjogrens syndrome?
A
MADFRED
Myalgia Arthralgia Dry mouth Fatigue Raynauds Phenomenon Enlarged Parotid Dry eyes
3
Q
what investigations can be done into Sjogrens syndrome?
A
- Anti Ro and Anti La antibodies
- RF and anti ds- DNA antibodies
- Schirmers test measures tear volume
- salivary gland biopsy may be needed
4
Q
how is Sjogrens treated?
A
Essentially symptomatic
Avoid dry or smoky atmospheres
Dry eyes–artificial tears
Dry mouth -artificial saliva, sugar free gum/pastilles
Skin emollients, vaginal lubricants
Immunosuppressants/steroids rarely needed
5
Q
what autoimmune conditions is Sjogrens associated with?
A
- coeliac
- primary billary cirrhosis
- autoimmune thyroid disease
