single factor causes Flashcards

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1
Q

what is the inheritance of genetic variants known as

A

Mandelian genetics

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2
Q

what did Mendel experiment on

A

mice, bees, hawk wind (a flowering plant) and peas

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3
Q

what did his work on peas show

A

showed that many characteristics showed repeatable patterns of inheritance

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4
Q

what were the seven traits/characteristics Mendel looked at

A
  • round or wrinkled
  • yellow or green
  • purple or white petals
  • green or yellow unripe pods
  • inflated or pinched ripe pods
  • axial or terminal flowers
  • short or long stems
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5
Q

what did Mendel predict

A
  • The concept of genes
  • That genes occur in pairs
  • That one gene of each pair is present in the gametes
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6
Q

what does gene mean

A

•Gene– a unit of heredity; a section of DNA sequence encoding a single protein

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7
Q

what does genome mean

A

the entire set of genes in an organism

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8
Q

what does the term alleles mean

A

two versions of a gene that occupies the same position on homologous chromosomes and that cover the same trait

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9
Q

what does the term locus mean

A

a fixed location on a strand of DNA where a gene is located

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10
Q

what does the term homozygous mean

A

having identical alleles (one from each parent) for a particular characteristic

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11
Q

what does the term heterozygous mean

A

having two different alleles for a particular characteristic

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12
Q

what does the term Hemizygous mean

A

having a single allele on a sex chromosome

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13
Q

what does the term Dominant mean

A

the allele of a gene that masks or suppresses the expression of an alternate allele; the trait appears in the heterozygous condition

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14
Q

what does the term Recessive mean

A

an allele that is masked by a dominant allele; does not appear in the heterozygous condition, only in homozygous

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15
Q

what does the term Genotype mean

A

the genetic makeup of an organisms

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16
Q

what does the term Phenotype mean

A

the physical appearance of an organism (Genotype + environment)

17
Q

what does the term single cross factor mean

A

Single factor cross: a genetic cross involving a single pair of genes (one trait); parents differ by a single trait

18
Q

what does P stand for

A

parental generation

19
Q

what does F1 stand for

A

filial generation; offspring from a genetic cross

20
Q

what does principle of dominance mean

A

e allele masked another, one allele was dominant over the other in the F1 generation

21
Q

what does principle of segregation

A

when gametes are formed, the pairs of hereditary factors (genes) become separated, so that each sex cell (egg/sperm) receives only one kind of gene

22
Q

what can dominant alleles show

A

incomplete or co-dominance

23
Q

what does the test cross allow

A

allows the determination of genotype of individuals with a dominant phenotype (are the homozygotes or heterozygotes?)

24
Q

what did Mendels experiment show

A

experiments on pea plants showed that genes are present in pairs and that each gamete only receives a single copy of each gene

25
Q

what is cystic fibrosis

A

a lethal genetic disease affecting Europeans
•Caused by mutant recessive gene carried by 1 in 20 people of European descent (12M)
•One in 400 Europeans couples will be both carriers of CF – 1 in 4 children will have it
•CF disease affects transport in tissues – mucus is accumulated in lungs, causing infections

26
Q

describe the inheritance of cystic fibrosis

A

if two parents carry the recessive gene of Cystic Fibrosis (c), that is, they are heterozygous (C c), one in four of their children is expected to be homozygous for cf and have the disease:
CC = normal
Cc = carrier, no symptoms
cc = has cystic fibrosis

27
Q

give an example of co-dominance

A

AB blood type

28
Q

what does heterozygous codominance alleles exhibit

A

exhibit the phenotypes of both alleles

29
Q

what does heterozygous incomplete dominant alleles produce

A

produce an intermediate phenotype

30
Q

different alleles present different glycoproteins on red blood cell so give some examples

A

O is recessive to A & B
•A & B show co-dominance
•AO and AA individuals exhibit the A glycoprotein
•BO and BB individuals exhibit the B glycoprotein
•AB individuals exhibit both the A and B glycoproteins

31
Q

what are different variants of genes called

A

alleles

32
Q

what can Alleles be

A

dominant or recessive

33
Q

give examples are draw out some single genetic factors

A

…..