Single Agent Adjuncts Flashcards
ALPHAGAN P .1%
Indication
Contraindication
Admin
AE
DDI
max IOP reduction
-reduction of IOP in OAG or OHT
-neonates and infants, hypersensitivity to brimonidine or tartrate or any components
-TID, 8 hours apart
-allergic conjunctivitis, conjunctival hyperemia, eye pruritus
-antihypertensives, cardiac glycosides, CNS depressants, TCAs, MAO inhibitors
-2-6 mm Hg
BRIMONIDINE .15%
Indication
Contraindication
Admin
AE
DDI
max IOP reduction
-reduction of IOP in OAG or OHT
-neonates and infants, hypersensitivity to brimonidine or any components
-TID, about 8 hours apart
-allergic conjunctivitis, conjunctival hyperemia, eye pruritus
-anti hypertensives, cardiac glycosides, CNS depressant, TCAs, MAO inhibitors
-2-6 mm Hg
BRIMONIDINE .2%
Indication
Contra
Admin
AE
DDI
max IOP reduction
-reduction of IOP in OAG or OHT
-neonates and infants, hypersensitivity to brimonidine or any components
-TID, about 8 hours apart
-oral dryness
-anti hypertensives, cardiac glycosides, CNS depressant, TCAs, MAO inhibitors
-4-6 mm Hg
AZOPT
Indication
Contra
Admin
AE
DDI
max IOP reduction
-reduce IOP
-hypersensitivity to brinzolamide or any components
-TID
-blurred vision, dysgeusia
-oral CAIs, high dose salicylate
-4-5 mm Hg
TRUSOPT
indication
contra
admin
AE
DDI
max IOP
-reduction of elevated IOP
-hypersensitivity to dorzolamide hydrochloride or any components
-TID
-ocular irritation
-oral CAIs, high dose salicylate
-3-5 mm Hg
TIMOLOL
indication
contra
admin
AE
DDI
max IOP
-treatment of elevated IOP
-bronchial asthma, severe COPD, cardiac cardiac problems, hypersensitivity to timolol maleate or any of its components
-QD
-blurred vision or instillation
-oral b-blockers, digitalis, alcium antagonists, catecholamine-depleting drugs, quindidine, clonidine, injectable epinephrine
-6 mm Hg
ISOPTO CARPINE
indication
contra
admin
AE
DDI
max IOP
-reduction of elevated IOP, management of AACG, prevention of post op IOP increase from laser surgery, induction of miosis
-none
-up to QID
-accommodative change, blurred vision, ocular irritation/pain, visual impairment, headache/brow ache
-none
-3-7 mm Hg
ALPHAGAN P .1%
active ingredient
brimonidine tartrate .1% or .15%
ALPHAGAN P .1%
class
a-agonist
ALPHAGAN P .1%
proposed MOA
reduce aqueous production and increase uveoscleral outflow
ALPHAGAN P .1%
bottle size availability
5 mL in a 10 mL bottle
10 mL in a 10 mL bottle
15 mL in a 15 mL bottle
BRIMONIDINE .15%
active ingredient
brimonidine tartrate .15%
BRIMONIDINE .15%
class
a-agonist
BRIMONIDINE .15%
proposed MOA
reduce aqueous production and increase uveoscleral outflow
BRIMONIDINE .15%
bottle size availability
5 mL in a 5 mL bottle
10 mL in 11 mL bottle
15 mL in a 15 mL bottle