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Additional Pharm Exam One (H, E &J) > Simmons Pharm 422 Exam 2 > Flashcards

Simmons Pharm 422 Exam 2 Flashcards

1
Q

Conditions treated by Augmentin (first choice) (4)

A 
Sinusitis 
Impetigo
Cellulitis 
Communication acquired pneumonia
Dog bite

SICC-DAWG!

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2
Q

Conditions treated with Amoxicillin First choice

4

A

Strep throat
Tonsillitis
Otitis media
Pharyngitis

STOP!

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3
Q

First choice antibiotic for meningitis

Ax to brain

A

Cefotaxime or Ceftriaxone

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4
Q

First line antibiotic C-diff

A

Metronidazole or Flagyl

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5
Q

Antibiotic for uncomplicated UTI in adult

A

Bactrim 3days or

Nitrofurantoin 7 days

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6
Q

First line antibiotic for MRSA

The good witch

A

Clindamycn

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7
Q

First line antibiotic treatment for Rickettsia, Lyme

A

Doxycycline

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8
Q

First line antibiotic treatment for pneumonia for mycoplasma

A

Azithromycin

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9
Q

First line antibiotic treatment for Community acquired pneumonia

A

Augmentin

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10
Q

First line antibiotic combo therapy for gonorrhea chlamydia infection

A

Ceftriaxone 250 mg IM

Azithromycin 1g ORAL

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11
Q

First line antibiotic treatment for pertussis

A

Azithromycin

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12
Q

Metronidazole (Flagyl) treats these two conditions

A

Bacterial vaginosis

C-diff

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13
Q

Antibiotics affecting protein synthesis

(Motl (y) crew

A

Macrolides
Oxazolidinones
Tetracyclines
Lincosamides

MOTLEY CREW

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14
Q

Antibiotics affect in Qt Prolongation

FM-am (3)

A

Fluoroquinolones
Macrolides
Anti-malarias
Amiodarone antipsychotics fluconazole

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15
Q

Drugs that affect G6PD

SAM CK

A

Sulfa drugs

aspirin

malaria drugs

high dose vitaminC

high-dose vitamin K

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16
Q

Methemoglobinemia (inducers)

A

Lidocaine spray and nitrates

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17
Q

Optional choices for impetigo or penicillin allergy

A

First second and third generation cephalosporins

Fluoroquinolones

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18
Q

Antibiotic treatment of UTI in pregnancy

A

Amoxicillin

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19
Q

Antibiotic used to treat UTI in children

A

Augmentin or cephalexin

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20
Q

Antibiotic treatment of UTI in geriatric

A

Bactrim
Levofloxacin

NO NITROFURANTOIN!

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21
Q

If allergy to amoxicillin what antibiotic will be used to treat strep throat?

A

Azithromycin

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22
Q

Which 2 antibiotics can cause C-diff infection?

The good witch
Brain biotics

A

Clindamycin and cephalosporins

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23
Q

Which two antibiotics absorption is impaired by dairy consumption

A

Tetracycline and Cipro

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24
Q

Which two antibiotics can cause peripheral neuropathy?

A

Nitrofurantoin

Zyvox

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25
In regard to absorption and pregnancy which functions are increased?
Skin penetration Gastric emptying Lung absorption
26
In re: to absorption in pregnancy, which 3 functions are reduced?
GI Motility gastric acid secretion gastric acidity
27
Blood volume, total body water, and cardiac output are blank in pregnancy in regard to distribution?
Increased
28
Uterine blood flow, volume of distribution, and fat distribution are all blank pregnancy in regard to distribution?
Increased
29
What one function in regard to distribution is decreased in pregnancy?
Plasma protein binding
30
And pregnancy drugs that are excreted primarily by the kidneys show a blank in elimination?
Increase
31
``` During pregnancy we want to prescribe drugs that are what in terms of : Protein fat Ionization status molecular weight ```
Highly protein bound Hydrophilic Ionized High molecular weight
32
Drugs to avoid during lactation
Chemotherapy Lithium Cyclosporin Methotrexate
33
Are insulin and heparin OK for pregnancy?
Yes
34
Meds to avoid during pregnancy
``` NSAIDs Coumadin Aspirin chemotherapy Ace inhibitors ARBS ```
35
Which antibiotics should be taken on an empty stomach
Levofloxacin Macrolides Penicillin
36
Flagyl should be taken with or without food?
With food
37
Myelosuppression Serotonin syndrome Peripheral neuropathy Which antibiotic can cause all three?
Linezolid (Zyvox)
38
Penicillin, cephalosporins, glycopeptides All inhibitors of what?
Beta lacatamase
39
Lincosamides Oxazoliddones Macrolides Tetracyclines All affect what in bacteria?
Protein synthesis
40
Fluoroquinolones Metronidazole Most of these affect what in bacteria replication?
DNA GYRASE
41
Sulfonomides Trimethoprim Nitrofurantoin All inhibit what in bacteria ?
Metabolic pathways
42
If spotting in follicular phase what adjustments need to be made in OCP?
More EE
43
Disulfiram reaction caused by these 2 antibiotics
Cephalosporins | Flagyl
44
Antibiotic used to tx syphilis and group A strep
Penecilin
45
6 conditions PCN treats UUP SOS
URI, pharyngitis, sinusitis, OM, STI, UTI
46
In PCN script what will decrease dose?
low GFR
47
Ampicillin and Sulbactam
Augmentin
48
Weaken cell wall causing bacteria to absorb water and rupture
penicillin
49
CSF action w/inflammation (3/4th)
Cephalosporins
50
Which antibiotics are nephrotoxic?
Cephalosporins, Glycopetides (Vanco)
51
The antibiotic class that Inhibits folic acid synthesis
Sulfonamides (Trimethoprim) Bactrim
52
community acquired MRSA 1st & 2nd line
Bactrim first, Clindamycin second due to causing C-diff
53
Levofloxacin, ciprofloxacin, moxifloxacin belong to what class?
Flouroquinolones
54
Levofloxacin should be taken...?
on an empty stomach
55
Special (renal) considerations when dosing Flouroquinolones
- Decrease dose is CrCl <50
56
Antibiotic that has a metallic taste
Matronidazole (Flagyl) | Flouroquinolones
57
Pregnancy Cat C/D (avoid 3rd trimester), Lactation: avoid Peds: only >2y/o
Bactrim
58
Antibiotic that can cause kernicterus in babies
Bactrim
59
Which antibiotics can cause Photosensitivity?
Tetracyclines Bactrim Flouroquinolones
60
Linezolid Ex: Zyvox is in what class antibiotic?
Oxazalidinones
61
what antiobiotic treats these? VRE, MRSA, TB, group A/B strep
Oxazalidinones | Linezolid Ex: Zyvox
62
Tetracycline is which bacteriocidal or bacteriostatic?
bacteriostatic
63
h. pylori antiobiotics
Tetracycline, - Clarithromycin
64
Erythromycin, azithromycin, clarithromycin (Class)?
Macrolides
65
Glycopeptides example
Vancomycin / Televancin
66
Lincosamides
Ex: Clindamycin
67
Options for cellulitis
Augmentin | Clindamycin
68
Excellent activity against MSSA, strep, H. flu, M. | catarrhalis, Neisseria meningitides, E. coli, Klebsiella, etc.
aminopenicillins
69
• Ineffective against gram-negative anaerobes such as MRSA
PCN
70
? are the treatment of choice for mycoplasma pneumonia
Macrolides

Additional Pharm Exam One (H, E &J) (2 decks)

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