Signs And Symptoms Of Respiratory Disease Flashcards

1
Q

What are the cardinal signs and symptoms of respiratory disease?

A

Breathlessness

Chest pain

Cough

Haemoptysis

Sputum

Wheeze / Stridor

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2
Q

What is breathlessness?

A

Subjective awareness of increased effort required for breathing
-Symptom rather than a sign
…But objective evidence of breathless may present (e.g. raised respiratory rate or use of accessory muscles)

Very common (often variably described)
-Common to all respiratory conditions
BUT not specific to resp conditions (e.g. anaemia, heart failure, obesity)

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3
Q

How does onset, timing and duration affect the differentials of breathlessness?

A

Instant-minutes: PE, acute asthma, pneumothorax, foreign body

Hours to Days: Pneumonia, acute exacerbation COPD, Pleural effusion (days)

Weeks to months: Pleural effusion (days), heart failure, lung cancer

Months to years: COPD, pulmonary fibrosis, anaemia

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4
Q

What things can you ask regarding breathlessness?

A

Triggers - allergies, cold weather..

Impact - stop you doing?

Exacerbating / relieving factors - position, cold weather, pets

Stable or getting worse

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5
Q

What could cause chest pain?

A

Pleural:

  • Infection (pleurisy)
  • Pneumothorax
  • PE (causing infarct)

Chest wall:

  • Rib fracture
  • Costochondritis
  • Shingles (varicella zoster)

Mediastinal structures:

  • MI
  • Pericarditis
  • Oesophaitis / GORD
  • Aortic dissection
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6
Q

Why are location character and exacerbating or releasing factors important when discussing chest pain?

A

It can help you work out the cause of the pain.

Central vs non-central

Cardiac vs “pleuritic”

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7
Q

What type of pain will irritation of the parietal pleural cause?

A

Irritation of the parietal pleural cause pain that is sharp, localised and referred to thoracic wall (intercostal nerve) or shoulder tip (phrenic nerve)

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8
Q

What is a cough?

A

A short, explosive expulsion of air triggered by mechano- or chemo-receptors within the airway.

There is forced expiratory effort against an initially closed glottis.

  • Build up intrathoracic pressure, followed by sudden opening of glottis.
  • Air expelled with high velocity!
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9
Q

Describe the cough reflex

A

Cough stimulus

Larynx / trachea / bronchi (receptors)

Afferent limb vagal nerves

Central cough control

Efferent limb motor nerves

Laryngeal respiratory muscles

Cough

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10
Q

What questions should you ask about a cough?

A

Productive or dry?

If productive - volume, colour blood?

Character e.g. “bovine,”(COPD) “seal like” (Croup)

Timing e.g. nocturnal, time of year

Cause: URTI (most common), could be a sign of more serious, chronic pathology.

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11
Q

What are some respiratory causes of a cough?

A

Anything that irritates the airways, lung parenchyma or pleura.

Infection (pneumonia
Bronchiectasis and CF
Pulmonary fibrosis
Lung cancer
Foreign body
Irritants e.g. smoking, occupational
Nasal and sinus disease (post-nasal drip)
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12
Q

What are some non-respiratory causes of a cough?

A

LV heart failure
GORD
Drugs e.g. ACE-inhibitors

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13
Q

What can the different colours of sputum tell you about cause?

A

Clear sputum - chronic bronchitis / COPD

Yellow / grey sputum (live / dead neutrophils) - infection

Large volumes (yellow / green) - Bronchiectasis

Haemoptysis - Potential red flag (TB, lung cancer)

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14
Q

What is a wheeze?

A

Abnormal breath sounds indicating narrowing within the airway causing turbulent flow.

High pitch, “musical”

Mostly on expiration - due to decrease pressure which narrows airway even more during expiration

Indicates narrowing in intrathoracic airways. e.g. bronchial smooth muscle, contraction, oedema, mucous

May only be audible with a stethoscope.

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15
Q

What is stridor?

A

Abnormal breath sounds indicating narrowing within the airway causing turbulent airflow.

High pitch, constant, loud

Mostly on inspiration

Indicates narrowing in extra thoracic airway - supra glottis, glottis, infraglottis or trachea

Narrowing exacerbated during expiration - because negative pressure.

Often audible without a stethoscope.

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16
Q

What do you look for upon inspection during a respiratory exam?

A

Raised respiratory rate

Cyanosis - central vs peripheral

Increased work of breathing - accessory muscles

Pursed lip breathing

Barrel shaped chest

Clubbing

17
Q

What do accessory muscles do?

A

Adequate ventilation not achieved by normal inspiration efforts

More effort required to move air through airways -e.g. narrowed

Accessory muscles help create greater negative intrathoracic pressure on inspiration. This pulls more air in and may cause tracheal tug.

Seen in patients with COPD and severe acute asthma.

18
Q

What is the difference in differentials between peripheral and central cyanosis?

A

Peripheral:

  • Can affect skin of feet, hands, nose and tips of ears.
  • Slow of blood to peripheries (due to vasoconstriction) increases the oxygen extraction so that more deoxygenated blood is present in that area.

Central cyanosis:

  • Affects lips and tongue (mucous membranes)
  • Indicates significant cardiac or respiratory cause
  • Caused by an increase in amount of deoxygenated Hb in blood arising at tissues (deoxygenated blood is leaving the heart)
19
Q

What is barrel shaped chest?

A

Associated with lung hyperinflation - seen in severe COPD

AP diameter > Lateral diameter

Chronic overinflation of lungs due to air trapping.

Hyperexpands the chest wall over time.

20
Q

What is pursed liped breathing and why is is useful?

A

Breathing out slowly through mouth with pursed lips

Commonly seen in COPD.

Pursing lips increases resistance to outflow expiration.

Maintains intrathoracic airway pressures allowing small airways to remain open for longer:
-Prolonging period for gas exchange and allowing more air to empty rather than trap.

21
Q

On palpation, what is suggestive of a respiratory disease?

A

Chest expansion

Symmetrically reduced:

  • Severe COPD
  • Diffuse pulmonary fibrosis

Asymmetrically reduced
-Indicated unilateral abnormality e.g. collapse, pneumothorax, effusion

22
Q

On percussion, what is suggestive of a respiratory disease?

A

Most of lung should normally be resonant (not if heart, liver..)

Dull to percuss = consolidation (solidification due to filling of lungs with solid (ish) material.)

Stony dull = pleural effusion

Hyperresonant = Area of increased air e.g. lung hyperinflation, pneumothorax

23
Q

On auscultation, what is suggestive of a respiratory disease?

A

Crackles (abrupt ‘snapping’ open of alveoli and small bronchi)
-Interrupted, non-musical
-Fine or coarse
Fine (soft, high pitch) = pulmonary fibrosis
Coarse (loud, low pitch) = COPD, bronchiectasis (air bubbling through mucous secretions, may reduce on coughing)

Pleural rub

  • Scratching or coarse sound
  • Inflammation of pleura e.g. pleurisy
24
Q

In a respiratory exam, what could clubbing indicate?

A

Lung cancer, CF, Bronchiectasis