Signalling Molecules Flashcards

1
Q

6 types of signalling molecules

A

Steroid hormones and nuclear receptor super family

NO CO

Neurotransmitters

Peptide hormones and growth factors

Cytokines

Eicasanoids

Phytohormones

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2
Q

NOR?

A

Nuclear organisation region

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3
Q

Steroids are polar or non-polar?

A

Non polar (can cross membrane)

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4
Q

Nature of NO and CO

A

Paracrine

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5
Q

Nature of NO and CO

A

Paracrine

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6
Q

Work of NO and CO

A

Vasodilator

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7
Q

Nature of neurotransmitters

A

Hydrophilic

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8
Q

Neurotransmitters act on …?

A

Ligand gated channel like Acetylcholine receptor and GPCR

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9
Q

Widest variety of signalling molecules?

A

Peptide hormones

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10
Q

Neuropeptides?

A

Endorphins, enkephelins

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11
Q

Work of neuropeptides?

A

Analgesic (pain-reducing)

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12
Q

Egf?

A

Epidermal GF (stimulation of cell proliferation)

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13
Q

Ngf?

A

Nerve growth factor (development and survival of neurons)

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14
Q

Pdgf

A

Platelet derived GF (make fibroblasts)

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15
Q

Work of cytokines?

A

Regulate dev and diff of blood cells and control the activity of lymphocytes during immune response.

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16
Q

Examples of Eicasanoids?

A

Prostaglandins, prostacyclins, thromboxanes, leukobrians

17
Q

Examples of Eicasanoids?

A

Prostaglandins, prostacyclins, thromboxanes, leukobrians

18
Q

Eicasanoids are synthesized from? And by?

A

Eicasanoids are synthesized from ARACHIDONIC ACID by CYCLOOXYGENASE.

19
Q

Cyclooxygenase works on?

A

Aspirin and NSAIDS (non-steroidal anti inflammatory drugs)

20
Q

Rooting is due to?

A

Auxin (a high c low)

21
Q

Shooting is done by?

A

Cytokinin (c high a low)

22
Q

Auxin examples?

A

Indole acetic acid
Naphthalene aa
Indole butyric acid
2,4-D

23
Q

Auxin examples?

A

Indole acetic acid
Naphthalene aa
Indole butyric acid
2,4-D

24
Q

Cytokinin exmaples?

A

BAP
Kinetic
Coconut water