Signalling Molecules Flashcards
6 types of signalling molecules
Steroid hormones and nuclear receptor super family
NO CO
Neurotransmitters
Peptide hormones and growth factors
Cytokines
Eicasanoids
Phytohormones
NOR?
Nuclear organisation region
Steroids are polar or non-polar?
Non polar (can cross membrane)
Nature of NO and CO
Paracrine
Nature of NO and CO
Paracrine
Work of NO and CO
Vasodilator
Nature of neurotransmitters
Hydrophilic
Neurotransmitters act on …?
Ligand gated channel like Acetylcholine receptor and GPCR
Widest variety of signalling molecules?
Peptide hormones
Neuropeptides?
Endorphins, enkephelins
Work of neuropeptides?
Analgesic (pain-reducing)
Egf?
Epidermal GF (stimulation of cell proliferation)
Ngf?
Nerve growth factor (development and survival of neurons)
Pdgf
Platelet derived GF (make fibroblasts)
Work of cytokines?
Regulate dev and diff of blood cells and control the activity of lymphocytes during immune response.
Examples of Eicasanoids?
Prostaglandins, prostacyclins, thromboxanes, leukobrians
Examples of Eicasanoids?
Prostaglandins, prostacyclins, thromboxanes, leukobrians
Eicasanoids are synthesized from? And by?
Eicasanoids are synthesized from ARACHIDONIC ACID by CYCLOOXYGENASE.
Cyclooxygenase works on?
Aspirin and NSAIDS (non-steroidal anti inflammatory drugs)
Rooting is due to?
Auxin (a high c low)
Shooting is done by?
Cytokinin (c high a low)
Auxin examples?
Indole acetic acid
Naphthalene aa
Indole butyric acid
2,4-D
Auxin examples?
Indole acetic acid
Naphthalene aa
Indole butyric acid
2,4-D
Cytokinin exmaples?
BAP
Kinetic
Coconut water