Signaling Pathways (Table 14-2) Flashcards

1
Q

N1 nicotinic ACh agonists

A

nicotine, decamethonium

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2
Q

N2 nicotinic ACh agonist

A

nicotine, TMA

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3
Q

M1, M2, M3, M4, M5 muscarinic ACh agonists

A

muscarine

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4
Q

alpha1-adrenergic agonist

A

phenylephrine

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5
Q

alpha2-adrenergic agonist

A

clonidine

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6
Q

alpha1- and alpha2-adrenergic NE vs Epi

A

NE > or = Epi

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7
Q

beta1-adrenergic agonist

A

dobutamine, isoproterenol

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8
Q

beta2-adrenergic agonist

A

terbutaline, isoproterenol

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9
Q

beta3-adrenergic agonist

A

isoproterenol

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10
Q

beta1- beta2- and beta3-adrenergic NE vs Epi

A

Epi > NE

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11
Q

N1 nicotinic ACh antagonist

A

d-tubocurarine, alpha-bungarotoxin

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12
Q

N2 nicotinic ACh antagonist

A

hexamethonium

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13
Q

M1 muscarinic ACh antagonist

A

atropine, pirenzepine

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14
Q

M2 muscarinic ACh antagonist

A

atropine, methoctramine

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15
Q

alpha1-adrenergic antagonist

A

phentolamine

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16
Q

alpha2-adrenergic antagonist

A

yohimbine

17
Q

beta1-adrenergic antagonist

A

metoprolol

18
Q

beta2-adrenergic antagonist

A

butoxamine

19
Q

beta3-adrenergic antagonist

A

SR-59320A

20
Q

M1, M3, M5 muscarinic ACh G protein

A

Galpha-q

21
Q

M2, M4 muscarinic ACh G protein

A

Galpha-i, Galpha-o

22
Q

alpha1-adrenergic G protein

A

Galpha-q

23
Q

alpha2-adrenergic G protein

A

Galpha-i

24
Q

beta1- beta2- and beta3-adrenergic G protein

A

Galpha-s

25
Q

D1 G protein

A

Galpha-s

26
Q

D2 G protein

A

Galpha-i

27
Q

M1, M2, M3 muscarinic ACh linked enzymes

A

PLC

28
Q

M2, M4 muscarinic ACh linked enzymes

A

adenyl cyclase

29
Q

alpha1-adrenergic linked enzymes

A

PLC

30
Q

alpha2-adrenergic linked enzyme

A

adenyl cyclase

31
Q

beta1- beta2- and beta3-adrenergic linked enzyme

A

adenyl cyclase

32
Q

D1, D2 linked enzyme

A

adenyl cyclase

33
Q

M1, M3, M5 muscarinic ACh second messenger

A

IP3, DAG

34
Q

M2, M4 muscarinic ACh second messenger

A

decreased intracellular cAMP concentrations

35
Q

alpha1-adrenergic second messenger

A

IP3, DAG

36
Q

alpha2-adrenergic second messenger

A

decreased intracellular cAMP concentrations

37
Q

beta1- beta2- and beta3-adrenergic second messenger

A

increased intracellular cAMP concentrations

38
Q

D1 second messenger

A

increased intracellular cAMP concentration

39
Q

D2 second messenger

A

decreased intracellular cAMP concentration