Signaling Pathways Of Endocrine Hormones

Question 1

cAMP

Answer 1

FLAT ChAMP

FSH
LH
ACTH
TSH

CRH
HCG
ADH (v2 receptors)
MSH
PTH

PLUS CALCITONIN, GHRH, GLUCAGON

Question 2

cGMP

Answer 2

BAD GraMPa

BNP
ANP
eDrf (nitric oxide)

All are Vasodilators

Question 3

IP3

Answer 3

GOAT HAG

GnRH
Oxytocin
ADH (v1 receptors)
TRH

Histamine (H1 receptors)
Angiotensin II
Gastrin

Question 4

Intracellular Receptors

Answer 4

PET CAT on TV

PROGESTERONE
ESTROGEN
TESTOSTERONE

CORTISOL
ALDOSTERONE
T3

T4
Vitamin D

All are non- water soluble

Question 5

Receptor Tyrosine Kinase

Answer 5

MAP Kinase and growth factors

Insulin
IGF1
FGF
PDGF
EGF

Question 6

Non-receptor tyrosine kinase

Answer 6

PIGGlETT

PROLACTIN
IMMUNOMODULATORS (il2, cytokines, il6, IFN)
GH
G-CSF
ERYTHROPOIETIN 
THROMBOPOETIN

Question 7

Rules to remember:

Answer 7

1) lipophillic hormones use intracellular receptors
2) major basil dilators use cGMP
3) FLAT hormones use GsPCR/ cAMP pathway
4) hormones involved in stimulation make use of the Gstinulatory Coyoled Receptor aka cAMP pathway

Ex. Epinephrine - bets cell stimulation
Ex. Glucagon - substitute for epinephrine when you overdose on bets blockers

4.5) norepinephrine makes use of the Gq/ip3 pathway to increase intracellular calcium, causing Vasoconstriction

5) GsCAMP - vasoldilation
Gq/ip3 - vasoconstriction

6) Gs:
FLAT
EPINEPHRINE
GLUCAGON
GHRH
CRH

Gq:
NOREPINEPHRINE 
GNRH
OXYTOSIN
ADH (v1 is for vasoconstriction using Gq, V2 is an aqua potion insertion into the principal cells using Gs)
TRH