signaling pathways of endocrine hormones

Question 1

FSH

Answer 1

cAMP

Question 2

LH

Answer 2

cAMP

Question 3

ACTH

Answer 3

cAMP

Question 4

TSH

Answer 4

cAMP

Question 5

CRH

Answer 5

cAMP

Question 6

hCG

Answer 6

cAMP

Question 7

ADH (V2 receptor)

Answer 7

cAMP

Question 8

MSH

Answer 8

cAMP

Question 9

PTH

Answer 9

cAMP

Question 10

calcitonin

Answer 10

cAMP

Question 11

GHRH

Answer 11

cAMP

Question 12

glucagon

Answer 12

cAMP

Question 13

histamine

Answer 13

cAMP (H2 receptor)

Question 14

BNP

Answer 14

cGMP

Question 15

ANP

Answer 15

cGMP

Question 16

EDRF

Answer 16

endothelium derived relaxing factor - eg NO- cGMP

Question 17

GnRH

Answer 17

IP3

Question 18

Oxytocin

Answer 18

IP3

Question 19

ADH (V1 receptor)

Answer 19

IP3- these are the receptors in blood vessels that are responsible for vasopressor action

Question 20

angiotensin II

Answer 20

IP3

Question 21

Gastrin

Answer 21

IP3

Question 22

Progesterone

Answer 22

intracellular receptor

Question 23

estrogen

Answer 23

intracellular receptor

Question 24

testosterone

Answer 24

intracellular receptor

Question 25

cortisol

Answer 25

intracellular receptor

Question 26

aldosterone

Answer 26

intracellular receptor

Question 27

T3/T4

Answer 27

intracellular receptor

Question 28

vitamin D

Answer 28

intracellular receptor

Question 29

insulin

Answer 29

receptor tyrosine kinase. MAP kinase.

Question 30

igf-1

Answer 30

receptor tyrosine kinase. MAP kinase.

Question 31

fgf

Answer 31

receptor tyrosine kinase. MAP kinase. fibroblast growth factor. e.g.: in achondroplasia there is constitutive activation of FGFR3 actually inhibits chondrocyte proliferation.

Question 32

pdgf

Answer 32

receptor tyrosine kinase- MAP kinase

Question 33

egf

Answer 33

receptor tyrosine kinase- MAP kinase

Question 34

prolactin

Answer 34

nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.

Question 35

immunomodulators (IL2, IL6, IFN)

Answer 35

nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.

Question 36

GH

Answer 36

nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.

Question 37

G-CSF

Answer 37

nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.

Question 38

EPO

Answer 38

nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.

Question 39

thrombopoietin

Answer 39

nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.