Signal Flashcards
Electrical synapse
Uses electrical signal to flow through gap junctions
Gap junctions
Bridges to connect neurons
Presynaptic cell
Axon terminals
Signal is coming from
Synaptic cell
Space between pre and post
Postsynaptic cell
Receives signal
Receptors on axon
AP in axon terminal
Ca2+ channel opens
Ca2+ flow’s in
Triggering exocytosis
Diffuses with it
Binds with Receptors on post cell
Response in post cell
Frequency modulation
Number of AP = Ca2+ releases
Stronger stimulus= more rate of APS
Fast synaptic potential
Rapid, short duration
Binds to Opens chemically gated ion channels
Alters flow in/ out of post synaptic cell
Slow synaptic potentials
Slower onset, long duration
Binds to G-protein coupled receptors
Alters membrane, modifies proteins, alters protein
7 major classes
Acetylcholine
Amines
Amino acids
Peptides
Purines
Gases
Lipids
Ligand
Chemical binding to another chemical
Different ligands may bind to same receptor
One ligand may bind to different receptors
Receptors down regulation
Drug tolerance
Decrease in receptor number
Receptor upregulation
Neuronal damage
Increase in receptor number
Signal Agonist
Activate receptors
Activates oxytocin receptors
Contractions