Side Effects Flashcards

1
Q

AE: flushing

A

Vancomycin, niacin, calcium channel blockers (dihyrdroperidine), adenosine

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2
Q

AE: coronary vasospasm

A

Cocaine, amphetamines, ergots, triptans

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3
Q

AE: dilated cardiomyopathy

A

Danorubicin, doxorubicin

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4
Q

AE: torsades de points

A

Sodium and potassium channel blockers, macrolides, haloperidol, protease inhibitors, choloquine

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5
Q

AE: thrombocytopenia

A

Heparin, cimetidine

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6
Q

AE: Agranulocytosis

A

Colchine, carbamazapine, clozapine, PTU, methimazole, dapsone

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7
Q

AE: aplastic anemia

A

Chlorampenicol, benzene, NSAIDs, PTU, methimazole

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8
Q

AE: Gray baby syndrome

A

Chlorampenicol

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9
Q

AE: hemolysis in G6PD def

A

“Spleen purges nasty inclusions from damaged cells”

Isoniazid, sulfonamides, primaquine, aspirin (high dose), ibuprofen, nitrofurantoin, dapsone, fava beans, naphthalene

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10
Q

AE: thrombosis

A

OC

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11
Q

AE: Pulm fibrosis

A

Amiodarone, busulfan, bleomycin

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12
Q

AE: cough

A

ACE inhibitors

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13
Q

AE: pseudomembranous colitis

A

Clindamycin, amoxicillin/ampicillin

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14
Q

AE: hepatic necrosis

A

Acetaminophen, halothane, mushrooms (Amanita phalloides), valproic acid

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15
Q

AE: hepatitis

A

isoniazid

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16
Q

AE: tertiary adrenal insufficiency

A

Corticosteroid withdrawal

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17
Q

AE: Gynecomastia

A

Spironolactone, THC, Alcohol, Cimetidine, Ketoconazole, Estrogens, Digoxin
“STACKED”

18
Q

AE: hot flashes

A

Tamoxifen, Clomiphene

19
Q

AE: hypothyroidism

A

Amiodarone, lithium, sulfonamides

20
Q

AE: Gout

A

Diuretics (loop and thiazide), niacin, cyclosporine, pyrazinamide

21
Q

AE: gingival hyperplasia

A

Phenytoin, verapamil

22
Q

AE: osteoporosis

A

Corticosteroids, heparin

23
Q

AE: Steven Johnson syndrome

A

Carbamazapine, lamotrigine, allopurinol, phenytoin, phenobarbital, penicillin, ethosuximide, RASH, sulfonamides
“CLAPPPERS”

24
Q

AE: Drug induced Lupus

A

Sulfonamides, Hydralazine, Isoniazid, Procainamide, Phenytoin
“SHIPP”

25
Q

AE: tendonitis

A

Fluoroquinolones

26
Q

AE: interstitial nephritis

A

NSAIDs, furosemide, anitbiotics

27
Q

AE: DI

A

Lithium, demeclocyline

28
Q

AE: fanconi syndrome

A

expired tetracycline

29
Q

AE: hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide

30
Q

AE: Parkinson like syndrome

A

Metoclopramide, antipsychotics, reserpine

31
Q

AE: Cinchonism

A

Quinidine, quinine

32
Q

AE: seizures

A

Bupropion, imipenem/cilastin, isoniazid, tramadol, metoclopramide, benzo/alcohol withdrawal

33
Q

AE: tardive dyskinesia

A

Antipsychotics, metoclopramide

34
Q

AE: disulfiram like reaction

A

Metronidazole, certain cephalosporins, probarbazine, first gen sulfonylureas, disulfiram

35
Q

AE: nephro + neuro

A

Aminoglycosides, cisplatin, polymixins

36
Q

AE: nephro + ototoxicity

A

Aminoglycosides, vanc, loop diuretics, cisplatin

37
Q

AE: anticholinergic effects

A

atropine, TCAs, H1 blockers, low potency neuroleptics

38
Q

AE: hyperglycemia

A

corticosteroids and protease inhibitors

39
Q

AE: megaloblastic anemia

A

Phenytoin, methotrexate, sulfa drugs

40
Q

AE: photosensitivity

A

Sulfonamides, Amiodarone, Tetracyclines

“SAT for a photo”

41
Q

Drugs with low therapeutic index

A

digoxin, lithium, warfarin, theophylline