Side Effects Flashcards
May cause sterile hemorrhagic cystitis
Cyclophosphamide
Intestinal epithelium, bone marrow suppression, renal tubular necrosis
Methotrexate
Nausea, anorexia, diarrhea, myelosuppression
Fluororuracil
Myelosuppression, neurotoxicity
Cytarabine
Bone marrow depression, vomiting, nausea, anorexia, jaundice
Mercaptopurine
Hematopoietic depression, GI disturbance
Hydroxyurea
Strongly myelosuppressive, epithelial ulcerations
Vinblastine
Alopecia, neuromuscular abnormalities (peripheral neuropathy), significantly less bone marrow suppression
Vincristine
Dose-limiting leukopenia, peripheral neuropathy, myalgia/arthralgia
Paclitaxel
Cardiomyopathy, bone marrow depression, alopecia, GI disturbances
Doxorubicin
Dose-related pulmonary toxicity, vesiculation of the skin, skin hyper pigmentation, minimal myelosuppression and immunosuppression
Bleomycin
Leukopenia, nausea, vomiting, diarrhea, alopecia
Etoposide
Bone pain
Filgrastim
Cardiomyopathy, hypersensitivity, infusion reactions
Trastuzumab
Nephrotoxicity, ototoxicity, peripheral neuropathy, electrolyte disturbances, nausea, vomiting, myelosuppression
Cisplatin