Side Effects Flashcards
Clonidine SE
Withdrawal hypertension
due to alpha 2 downregulation
DOC Rx phentolamine
B blockers CNS SE
Lipid soluble- cross BBB
depression
insomnia
nightmares
Beta 2 agonist SE
Salbutamol etc
Palpitations
tremor
HYPERglycemia ***
hypokalemia
Prostaglandin analogues SE and CI
Lactanoprost
Iris pigmentation
trichomegaly
Dry/sandy eyes
cystoid macular edema
CI -
uveitis
herpetic keratitis
Timolol SE
NLD obstruction
Metipranolol SE
Granulomatous Anterior Uveitis
Epinephrine S/E
topical eye
Black pigmentation of conjunctiva
(dt coversion to melanin)
Apraclonidine SE
Alpha 2 agonists in eye
Due to Alpha —- constriction of ms and blood vs
Lid retraction
Mydriasis (ciliary ms constrict)
Conjunctival blanching
Brimonidine SE
Alpha 2 agonists in eye
Crosses BBB
Neonates: apnoea
Drowsiness/sleeping tendency
Hypotension
Pilocarpine SE
pilo (drink)- BAR
brow ache
accomodation spasm
retinal dettachment