Side Effects Flashcards
SSRI
Warning: QTc prolongation (less with sertraline), SIADH/hyponatremia, fall risk, bleeding
SE: somnolence, insomnia, nausea, weakness, tremor, dizziness, decreased libido, erectile dysfunction
SNRI
Warning: SIADH/hyponatremia, falls, bleeding
SE from NE: tachycardia, hypertension, dilated pupils, dry mouth, sweating, constipation
SE: somnolence, insomnia, nausea, weakness, tremor, dizziness, decreased libido, erectile dysfunction
Secondary Amine TCA (Nortriptyline)
Cardiotoxicity: QTc prolongation, orthostasis, tachycardia
Anticholinergic: dry mouth, constipation, blurred vision, urinary retention, confusion
SE: sedation, weight gain, vivid dreams, risk of falls
Tertiary Amine TCA (Amitryptiline)
Cardiotoxicity: QTc prolongation, orthostasis, tachycardia
Anticholinergic: dry mouth, constipation, blurred vision, urinary retention, confusion
* higher risk*
SE: sedation!!!, weight gain!!!, vivid dreams, risk of falls
Buproprion (Wellbutrin)
CI: seizure disorder, history of anorexia/bulemia
Warning: neuropsychiatric ADR
SE: dry mouth, CNS stimulation (insomnia, restlessness), tremors/seizures, weight loss
Mirtazapine (Remeron)
Warning: anticholinergic effect, QTc prolongation, blood dyscrasias, CNS depression
SE: Sedation, increased appetite, weight gain
Trazodone
Sedation, Orthostasis, Sexual dysfunction, priapism
1st generation antipsychotics
Warning: QTc prolongation, Anticholinergic effects, CNS depression, EPS, NMS, hyperprolactinemia
SE: sedation, dizziness, anticholinergic effects
Ariprazole (Abilify)
Akathisia, Activation (more than sedation), QTc prolongation
***lower risk of metabolic syndrome and weight gain
Clozapine (Clozaril)
REMS for neutropenia and agranulocytosis (to start therapy ANC must be > or = 1500)
SE: seizures!!, constipation, metabolic syndrome, hypersalivation (sialorrhea)
Lurasidone (Latuda)
Somnolence, EPS, nausea
**lower risk of of metabolic syndrome
Olanzapine (Zyprexa)
Somnolence, metabolic syndrome, orthostasis
Paliperidone (Invega)
Hyperprolactin, EPS, Metabolic Syndrome, QTc prolongation
Quetiapine (Seroquel)
Somnolence, metabolic syndrome, orthostasis
**lower EPS symptoms
Risperidone (Risperdal)
Hyperprolactin, EPS, QTc prolongation