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Psychiatric Conditions > Side Effects > Flashcards

Side Effects Flashcards

1
Q

SSRI

A

Warning: QTc prolongation (less with sertraline), SIADH/hyponatremia, fall risk, bleeding

SE: somnolence, insomnia, nausea, weakness, tremor, dizziness, decreased libido, erectile dysfunction

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2
Q

SNRI

A

Warning: SIADH/hyponatremia, falls, bleeding

SE from NE: tachycardia, hypertension, dilated pupils, dry mouth, sweating, constipation

SE: somnolence, insomnia, nausea, weakness, tremor, dizziness, decreased libido, erectile dysfunction

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3
Q

Secondary Amine TCA (Nortriptyline)

A

Cardiotoxicity: QTc prolongation, orthostasis, tachycardia

Anticholinergic: dry mouth, constipation, blurred vision, urinary retention, confusion

SE: sedation, weight gain, vivid dreams, risk of falls

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4
Q

Tertiary Amine TCA (Amitryptiline)

A

Cardiotoxicity: QTc prolongation, orthostasis, tachycardia

Anticholinergic: dry mouth, constipation, blurred vision, urinary retention, confusion
* higher risk*

SE: sedation!!!, weight gain!!!, vivid dreams, risk of falls

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5
Q

Buproprion (Wellbutrin)

A

CI: seizure disorder, history of anorexia/bulemia

Warning: neuropsychiatric ADR

SE: dry mouth, CNS stimulation (insomnia, restlessness), tremors/seizures, weight loss

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6
Q

Mirtazapine (Remeron)

A

Warning: anticholinergic effect, QTc prolongation, blood dyscrasias, CNS depression

SE: Sedation, increased appetite, weight gain

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7
Q

Trazodone

A

Sedation, Orthostasis, Sexual dysfunction, priapism

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8
Q

1st generation antipsychotics

A

Warning: QTc prolongation, Anticholinergic effects, CNS depression, EPS, NMS, hyperprolactinemia

SE: sedation, dizziness, anticholinergic effects

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9
Q

Ariprazole (Abilify)

A

Akathisia, Activation (more than sedation), QTc prolongation

***lower risk of metabolic syndrome and weight gain

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10
Q

Clozapine (Clozaril)

A

REMS for neutropenia and agranulocytosis (to start therapy ANC must be > or = 1500)

SE: seizures!!, constipation, metabolic syndrome, hypersalivation (sialorrhea)

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11
Q

Lurasidone (Latuda)

A

Somnolence, EPS, nausea

**lower risk of of metabolic syndrome

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12
Q

Olanzapine (Zyprexa)

A

Somnolence, metabolic syndrome, orthostasis

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13
Q

Paliperidone (Invega)

A

Hyperprolactin, EPS, Metabolic Syndrome, QTc prolongation

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14
Q

Quetiapine (Seroquel)

A

Somnolence, metabolic syndrome, orthostasis

**lower EPS symptoms

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15
Q

Risperidone (Risperdal)

A

Hyperprolactin, EPS, QTc prolongation

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16
Q

Ziprasidone (Geodon)

A

QTc prolongation!!!

17
Q

Lithobid

A

Lithium

Warning: Serotonin Syndrome
SE: GI upset, cognitive effects, tremor, thrist, weight gain, hypothyroidism, cardiac abnormalities, hypercalcemia, blue-grey skin

Toxicity:
> 1.5 mEq/L - ataxia, tremor, vomiting
> 2.5 mEq/L - CNS depression, arrhythmia, seizures

18
Q

Ritalin (IR)

A

Methylphenidate

SE: insomnia, decreased appetite, weight loss, HA, irritability

19
Q

Stimulants for ADHD

A

CI: use with MAO inhibitors
Warning: High HR and BP, serious CV events, new onset of pyschosis, serotonin syndrome

20
Q

Concerta OROS

A

Methylphenidate

SE: insomnia, decreased appetite, HA, weight loss, irritability

GHOST tablet

21
Q

Adderall

A

Dextroampetamine/Ampetamine

BW: misuse can cause sudden death
***do not take with acidic foods like juice!

22
Q

Vyvanse

A

Lisdexamfetamine
Low abuse potentional!
All normal stimulant side effects

23
Q

Strattera

A

Atomoxetine
BW: suicide
CI: MAO inhibitor use
Warning: aggressive behavior, psychosis

SE: decreased appetite, somnolence, insomnia, dry mouth, hypertension, tachycardia

24
Q

Kapvay

A

Clonidine ER
Dose-dependent CV events (hypotension, bradycardia, orthostatis)

SEDATION
**do not discontinue abruptly due to rebound HTN

SE: dry mouth, somnolence, dizziness, constipation

25
Q

Ambien

A

Zolpidem
BW: sleep walking or sleep driving
Warning: CNS Depression
Abuse potential C IV

SE: somnolence, dizziness, ataxia, headache, parasomnias (unusual actions while sleeping!)

26
Q

Lunesta

A

Escopiclone
Warning: CNS depression

SE: somnolence, dizziness, ataxia, headache, parasomnias (unusual actions while sleeping!)

27
Q

Sulvorexant
C-IV

A

Orexin Receptor Antagonists
CI: Nacrolepsy!!!!!
Warning: suicide
SE: somnolence

28
Q

Doxepin

A

Tricyclic Antidepressant

BW: suicide
CI: MAO inhibitor
SE: anticholineric, somnolence

29
Q

Ramelteon

A

Melatonin Receptor Agonists

SE: somnolence

30
Q

Restoril

A

Temazepam

C-IV

SE; drowsiness, fall risk, cognitive impairment

**BEERS Criteria

31
Q

Modafinil

A

Tx of Narcolepsy
C-IV
SE: rash, anxiety, HA, insomnia

32
Q

Sodium oxybate (Xyrem)

A

Tx for Nacrolepsy
C-III
SE: REMS for strong CNS depressant

33
Q

Which antipsychotics have the MOST metabolic risk?

A

Clozapine
Olanzapine
Quetiapine

34
Q

Which antipsychotics have the LOWEST metabolic risk?

A

Ariprazole
Ziprasidone

35
Q

What antipsychotic has the greatest QTc risk?

A

Ziprasidone

36
Q

Which antipsychotics have the highest prolactin risk?

A

Respiridone
Paliperidone

37
Q

What antipsychotic has the greatest risk for seizures?

A

Clozapine

Psychiatric Conditions (3 decks)

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