Side Effects Flashcards

1
Q

Side Effects of COCP

A

Headache
N&V
Breast tenderness
VTE

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2
Q

Side Effects of POP

A

Acne

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3
Q

Side Effects of Heparin

A

Haemorrhage
Thrombocytopenia
Skin Reaction
Hyperkalaemia

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4
Q

Side Effects of Aspirin

A

Dyspepsia
Gastric Ulcers
Fe Deficiency Anaemia
Haemorrhage (esp GI)

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5
Q

Side Effects of Statins

A

Arthralgia, Myalgia, Asthenia & Headaches (possibly incr CK)
Diarrhoea, Constipation & Nausea
Thrombocytopenia
Dizziness

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6
Q

Side Effects of Opioids

A

Arrhythmias
Constipation & Urinary Retention
Respiratory Depression and Drowsiness
Nausea
Dry Mouth
Miosis

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7
Q

Side Effects of ACEi

A

Angioedema
Cough & Dry Mouth
Hypotension
Renal Impairment
Hyperkalaemia
Palpitations

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8
Q

Side Effects of ARB

A

Hyperkalaemia
Renal Impairment
Hypotension

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9
Q

Side Effects of Loop Diuretics

A

Dizziness, headache, metabolic alkalosis, muscle spasm, hyponatraemia, hypokalaemia

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10
Q

Side Effects of NSAIDs

A

Worsening of asthma
Incr in thrombotic events
Gastric ulcers
Worsening of renal failure

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11
Q

Side Effects of Clozapine

A

Agranulocytosis

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12
Q

Side Effects of typical (first generation) anti psychotics

A

Extrapyramidal side effects;
- Parkinsonian sx e.g. bradykinesia & tremor
- Dystonia
- Akathisia
- Tardive Dyskinesia

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13
Q

Side effects of antipsychotics

A

Hyperprolactinaemia (sexual dysfunction, decr bone mineral density, menstrual disturbances, breast enlargement, galactorrhoea)
Prolonged QT
Arrhythmia
Postural Hypotension
Weight gain
Neuroleptic malignant syndrome - hyperthermia, fluctuating GCS, muscle rigidity, tachy, sweating, labile BP)

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14
Q

Side effects of atypical (second generation) antipsychotics

A

Hyperglycaemia and diabetes

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15
Q

Side Effects of antidepressants

A

Hyponatraemia (esp SSRIs)
Suicidal behaviour
Serotonin syndrome - tremor, hyperreflexia, clonus, rigidity, tachy, BP changes, hyperthermia, shivering, agitation, confusion)

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16
Q

Side effects of Amitriptyline hydrochloride

A

Anticholinergic syndrome - incr HR and BP, flushed, anhidrosis, fever, decr UO / salivation, mydriasis
drowsiness
prolonged QT

17
Q

Side effects of tricyclic antidepressants

A

Antimuscarinic - dry mouth, constipation, decr UO, blurred vision, agitation
Drowsiness

18
Q

MAOI side effects

A

Hypertensive crisis
Hepatotoxicity

19
Q

Mirtazapine side effects

A

incr appetite
drowsiness
dry mouth
incr weight
constipation / diarrhoea
postural hypotension

20
Q

BB side effects

A

Bradycardia
Dizzy
Dry eyes / visual impairment
ED
HF
Headache
Paraesthesia
Peripheral coldness
PVD
Rash
GI upset

21
Q

CBB side effects

A

Abdo pain / nausea / vomiting
Flushing
Headache
Peripheral Oedema
Skin reactions
Tachycardia

22
Q

Bisphosphonates side effects

A

Bone, joint and muscle pain
GI upset
Hypocalcaemia
Atypical femoral fracture

23
Q

mineralocorticoid (aldosterone) side effects

A

HTN
Na retention
H2O retention
K+ loss
Ca2+ loss

24
Q

What drugs can cause serotonin syndrome?

A

SSRIs
SNRIs
Triptans
Tricyclic antidepressants
MAOIs
Lithium
Codeine, Fentanyl, Tramadol
Ritonavir abx
Illicit drugs
St johns wort

25
Q

Rifampicin side effect

A

colours tears, sweat and urine an orange / red

26
Q

What are the symptoms of anaphlyaxis?

A

Angioedema
Urticaria
Hypotension
bronchospasm

27
Q

If someone is allergic to penicillin, what other abx may they be allergic to?

A

Beta lactams
Cephalasporins (esp 1st and 2nd gen - cefalexin an cefuroxime. Caution with other gens)
Caution with carbapenems

28
Q

What drugs are common sources of drug allergy?

A

Chlorhexidine
NSAIDs
muscle relaxants (rocuronium)
opioid analgesics
penicillin and other beta lactams
plasma expanders
radiocontrast media

29
Q

What drugs can cause hyper K+?

A

ACEi
Acute digoxin OD
ARB
Heparin and LMWH
NSAIDs
Penicillins
K+ sparing diuretics
K+ supplements
Trimethoprim

30
Q

Fast infusion of vancomycin side effects?

A

Red man syndrome
cardiac arrest
cardiogenic shock

31
Q

S/E of carbimazole?

A

Bone marrow suppression resulting in agranulocytosis
Haemolytic anaemia
SCARS
thrombocytopenia

32
Q

S/E of sodium valporate

A

Pancreatitis
Osteoporosis (often prescribed + Vit D)
thrombocytopenia
movement disorders