Side Effects Flashcards

1
Q

Side Effects of COCP

A

Headache
N&V
Breast tenderness
VTE

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2
Q

Side Effects of POP

A

Acne

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3
Q

Side Effects of Heparin

A

Haemorrhage
Thrombocytopenia
Skin Reaction
Hyperkalaemia

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4
Q

Side Effects of Aspirin

A

Dyspepsia
Gastric Ulcers
Fe Deficiency Anaemia
Haemorrhage (esp GI)

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5
Q

Side Effects of Statins

A

Arthralgia, Myalgia, Asthenia & Headaches (possibly incr CK)
Diarrhoea, Constipation & Nausea
Thrombocytopenia
Dizziness

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6
Q

Side Effects of Opioids

A

Arrhythmias
Constipation & Urinary Retention
Respiratory Depression and Drowsiness
Nausea
Dry Mouth
Miosis

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7
Q

Side Effects of ACEi

A

Angioedema
Cough & Dry Mouth
Hypotension
Renal Impairment
Hyperkalaemia
Palpitations

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8
Q

Side Effects of ARB

A

Hyperkalaemia
Renal Impairment
Hypotension

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9
Q

Side Effects of Loop Diuretics

A

Dizziness, headache, metabolic alkalosis, muscle spasm, hyponatraemia, hypokalaemia

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10
Q

Side Effects of NSAIDs

A

Worsening of asthma
Incr in thrombotic events
Gastric ulcers
Worsening of renal failure

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11
Q

Side Effects of Clozapine

A

Agranulocytosis

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12
Q

Side Effects of typical (first generation) anti psychotics

A

Extrapyramidal side effects;
- Parkinsonian sx e.g. bradykinesia & tremor
- Dystonia
- Akathisia
- Tardive Dyskinesia

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13
Q

Side effects of antipsychotics

A

Hyperprolactinaemia (sexual dysfunction, decr bone mineral density, menstrual disturbances, breast enlargement, galactorrhoea)
Prolonged QT
Arrhythmia
Postural Hypotension
Weight gain
Neuroleptic malignant syndrome - hyperthermia, fluctuating GCS, muscle rigidity, tachy, sweating, labile BP)

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14
Q

Side effects of atypical (second generation) antipsychotics

A

Hyperglycaemia and diabetes

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15
Q

Side Effects of antidepressants

A

Hyponatraemia (esp SSRIs)
Suicidal behaviour
Serotonin syndrome - tremor, hyperreflexia, clonus, rigidity, tachy, BP changes, hyperthermia, shivering, agitation, confusion)

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16
Q

Side effects of Amitriptyline hydrochloride

A

Anticholinergic syndrome - incr HR and BP, flushed, anhidrosis, fever, decr UO / salivation, mydriasis
drowsiness
prolonged QT

17
Q

Side effects of tricyclic antidepressants

A

Antimuscarinic - dry mouth, constipation, decr UO, blurred vision, agitation
Drowsiness

18
Q

MAOI side effects

A

Hypertensive crisis
Hepatotoxicity

19
Q

Mirtazapine side effects

A

incr appetite
drowsiness
dry mouth
incr weight
constipation / diarrhoea
postural hypotension

20
Q

BB side effects

A

Bradycardia
Dizzy
Dry eyes / visual impairment
ED
HF
Headache
Paraesthesia
Peripheral coldness
PVD
Rash
GI upset

21
Q

CBB side effects

A

Abdo pain / nausea / vomiting
Flushing
Headache
Peripheral Oedema
Skin reactions
Tachycardia

22
Q

Bisphosphonates side effects

A

Bone, joint and muscle pain
GI upset
Hypocalcaemia
Atypical femoral fracture

23
Q

mineralocorticoid (aldosterone) side effects

A

HTN
Na retention
H2O retention
K+ loss
Ca2+ loss

24
Q

What drugs can cause serotonin syndrome?

A

SSRIs
SNRIs
Triptans
Tricyclic antidepressants
MAOIs
Lithium
Codeine, Fentanyl, Tramadol
Ritonavir abx
Illicit drugs
St johns wort

25
Rifampicin side effect
colours tears, sweat and urine an orange / red
26
What are the symptoms of anaphlyaxis?
Angioedema Urticaria Hypotension bronchospasm
27
If someone is allergic to penicillin, what other abx may they be allergic to?
Beta lactams Cephalasporins (esp 1st and 2nd gen - cefalexin an cefuroxime. Caution with other gens) Caution with carbapenems
28
What drugs are common sources of drug allergy?
Chlorhexidine NSAIDs muscle relaxants (rocuronium) opioid analgesics penicillin and other beta lactams plasma expanders radiocontrast media
29
What drugs can cause hyper K+?
ACEi Acute digoxin OD ARB Heparin and LMWH NSAIDs Penicillins K+ sparing diuretics K+ supplements Trimethoprim
30
Fast infusion of vancomycin side effects?
Red man syndrome cardiac arrest cardiogenic shock
31
S/E of carbimazole?
Bone marrow suppression resulting in agranulocytosis Haemolytic anaemia SCARS thrombocytopenia
32
S/E of sodium valporate
Pancreatitis Osteoporosis (often prescribed + Vit D) thrombocytopenia movement disorders