Side Effects Flashcards
Red Man Syndrome
Glycopeptides
Grey Baby Syndrome
Chloramphenicol
Ototoxicity, Cochlear and Vestibular Toxicity
Aminoglycosides
Red/orange urine, sweat and tears
Rifampin
Crystalluria, Steven-Johnsons and TEN
Sulfonamides
Blood Dyscrasias (abnormalities), Megoblastic Anaemia (Folate Deficiency), Kernicterus Precipitation (bilirubin precipitation and subsequent damage to brain motor areas)
Sulfonamides
Prolonged QT
Quinolones
Reversible Fanconi Syndrome (when consuming expired tablets of this class)
Tetracyclines
Phototoxicity, Children Stunted Growth, Pseudotumour cereberi, Hepato and Nephrotoxicity
Tetracyclines
Cholestatic Jaundice, QT Prolonged, Reversible Hearing Impairment
Macrolides (erythromycin in particular)
Cross allegenicitiy with Pencillins, Bleeding Disorders reversible with Vitamin K, interstitial nephritis and tubular necrosis.
Cephalosporins (1st and 2nd gen in particular)
Jarish-Herxheimer Reactions
Pencillins
Withdrawn due to extreme nephrotoxicity
Methicillin
Exacerbates MG, Haemlysis (G6PD Deficiency), Hypoglycaemia, Cardiac Conduction issues and Cinchonism (condition name for overdose of this drug), Veritgo
Quinine/Quinidine (anti-malarial)
Pseudomembranous Colitis and Skin Rashes
Lincosamides
Ototoxicity and Nephrotoxiticty
Glycopeptides
Taste alterations, Thrombocytopaenia with long term use, Irreversible peripheral neuropathies and optic neuritis after 28 days, use with caution with MAO and other serotingergic drugs.
Oxazolidinones
Aplastic Anaemia
Chloramphenicol
Neurological Imairement and Neuromuscular Blockade
Polypeptides (Polymyxin B Colistin, Bacitracin, Tyrothricin)
Hyperbilirubinaemia, Arthralgia and Myalgia, CYP3A4 inhbitor (affects other drug metabolism in liver)
Streptogramnins
Dark brown urine due to metabolites and Peripheral neuritis
Nitrofuroantoin.
Orange red urine, skin pigmentation
Phenazopyridine
Myelosupression, Hypotension, Somnolence
Thalidomide
Cough, Bronchospasm, Hypotension, Increased serum creatine
Pentamidine (Pneumo Jiro)
Elevation in transaminases and burning sensation
Ayclovir
Yellow teeth, bones, (or grey), and enamel hypoplasia
Tetracyclines
Black Hairy Tongue
Amoxillin (and some other Pencillins)
Aortic Dissection
Quinolones (ciprofloxacin)
MG exacerbations and tongue discolouration
Macrolides
Thrombophlebitis (thrombus induced inflammation of veins)
Carbapenems (meropenem)
Cerebellar Syndrome and metallic taste
Metranidazole (Nitrazole class)
Glossitis, altered taste, jaundice
Lipopeptides
Alopecia, Pellagra, Pancreatitis, Lupus, Optic atrophy
Isoniazid
Hyperhidrosis, Angiodema, CR Distress
Fluconazole
Alopecia, SCARs, Serotonin syndrome, bone marrow depression, discoloured teeth and lactic acidosis
Linezolid
Heals C. Dificle
Metranidazole
Causes C. Dificle
Lincosamides