SIADH vs. DI

Question 1

How does Syndrome of Inappropriate Antidiuretic Hormone (SIADH) affect urine?

Answer 1

Urine chemistry = concentrated

As urine volume decreases the urine osmolality increases

Question 2

How does Syndrome of Inappropriate Antidiuretic Hormone (SIADH) affect blood?

Answer 2

Blood chemistry = dilute

Volume increases the blood osmolality decreases

Question 3

Treatment for Syndrome of Inappropriate Antidiuretic Hormone (SIADH)

Answer 3

1. Restrict fluid

2. Demeclocycline causes excessive urine output

Question 4

What does Syndrome of Inappropriate Antidiuretic Hormone (SIADH) cause?

Answer 4

Fluid volume excess causing cerebral edema, seizures > high fall risk

Question 5

How does Diabetes Insipidus affect urine?

Answer 5

Urine = dilute
Volume increases the osmolality decreases
-Decreased urine specific gravity and osmolality

Question 6

How does Diabetes Insipidus affect blood?

Answer 6

Blood = concentrated

Volume decreases the osmolality increases

Question 7

What does Diabetes Insipidus cause?

Answer 7

Fluid volume deficit > sensory/perception > visual changes

Question 8

Treatment for Diabetes Insipidus

Answer 8

1. Encourage fluids

2. Desmopressin (DDAVP) causes increase water reabsorption