SIADH Flashcards
1
Q
Where is ADH produced? Where is it secreted?
A
Produced in hypothalamus
Secreted by posterior pituitary
2
Q
What is the function of ADH?
A
Stimulates water reabsorption (in the collecting duct)
3
Q
What are the clinical/biochemical features of SIADH?
A
- Symptoms are nonspecific
- Main biochemical finding is hyponatraemia, which may present with reduced consciousness/seizures if severe
4
Q
Describe the management of SIADH
A
- Treat underlying cause
- 1st line: fluid restriction
- 2nd line: tolvaptan (specialist use only)
5
Q
What are the causes of SIADH?
A
SIADH:
- Small cell lung cancer
- Infection
- Abscess
- Drugs, e.g. carbamazepine, SSRIs
- Head injury
