Shock Drugs

Question 1

first line for shock

Answer 1

dopamine and norepinephrine

Question 2

dopamine dosing

Answer 2

1-3 mcg/kg/min
3-10 mcg/kg/min
10-20 mcg/kg/min

Question 3

low dopamine dosing receptors

Answer 3

mainly DA

some B1

Question 4

low dopamine MOA

Answer 4

vasodilation of arteries (renal, mesenteric, cerebral, and coronary)
natriuretic response

Question 5

low dopamine monitoring

Answer 5

evidence does not support use for renal protection

Question 6

med dose dopamine receptors

Answer 6

mostly B1

Question 7

med dose dopamine MOA

Answer 7

increase contractility and HR

Question 8

med dose dopamine monitoring

Answer 8

can induce tachyarrhythmias

may complement vasoconstrictive effects of NE

Question 9

high dose dopamine receptors

Answer 9

mostly a1

Question 10

high dose dopamine moa

Answer 10

increase SVR

Question 11

high dose dopamine monitoring

Answer 11

renal blood flow effects lost

Question 12

NE dosing

Answer 12

2-20 mcg/min

Question 13

NE receptors

Answer 13

mostly a1

some b1

Question 14

NE moa

Answer 14

increase SVR

small increase in HR and contractility

Question 15

NE monitoring

Answer 15

decrease renal perfusion

CO and LV function decrease at high doses

Question 16

Epi dosing

Answer 16

1-10 mcg/min

Question 17

epi receptors

Answer 17

works in both a1 and b1

Question 18

epi moa

Answer 18

increases SVR, HR, and contractility

Question 19

epi monitoring

Answer 19

watch for tachyarrhythmias

Question 20

phenylephrine dosing

Answer 20

30-300 mcg/min

Question 21

PE receptors

Answer 21

only a1

Question 22

pe moa

Answer 22

increased svr

Question 23

pe monitoring

Answer 23

minimal cardiac activity

preferred in patients w history of arrhythmias

Question 24

vaso dosing

Answer 24

0.03-0.04 units/min

Question 25

vaso receptors

Answer 25

NONE

Question 26

vaso moa

Answer 26

non-adrenergic | increases SVR by stimulation of V1 smooth muscle receptors (causes vasoconstriction)

Question 27

vaso monitoring

Answer 27

do not titrate above state dose (too much vasoconstriction) | effective in acidosis and hypoxia

Question 28

dobutamine dosing

Answer 28

2-20 mcg/kg/min

Question 29

dobutamine receptors

Answer 29

mostly b1

Question 30

dobutamine moa

Answer 30

increase HR and CO

Question 31

dobutamine monitoring

Answer 31

primarily used for cardiogenic shock | can induce tachyarrhythmias

Question 32

milrinone dosing

Answer 32

0.35-0.75 mcg/kg/min

Question 33

milrinone receptors

Answer 33

NONE

Question 34

milrinone moa

Answer 34

inhibits PDE in cardiac and vascular tissue decreases preload and afterload which.. increases contractility and CO

Question 35

milrinone monitoring

Answer 35

inodilator renal function should be monitored can cause arrhythmias

Question 36

AT 2 dosing

Answer 36

20-40 ng/kg/min

Question 37

at 2 receptors

Answer 37

NONE

Question 38

at 2 moa

Answer 38

``` causes vasoconstriction increases aldosterone (increases BP) ```

Question 39

at 2 monitoring

Answer 39

thrombotic event | patient should respond within minutes