Shock 3

Question 1

General function of
1. Alpha 1
2. Beta 1
3. Beta 2
receptors

Answer 1

1. Peripheral vasoconstriction
2. Increase contraction (inotropy), increase SA node rate (chronotropy), increase AV conduction (dromotropy)
3. Inotropy, bronchodilation

Question 2

Norepinephrine

Answer 2

Recommended as first line agent for supportive care in most patients with shock NYD
Doesn’t help hemorrhagic shock though

Question 3

Vasopressin

Answer 3

ADH analog
Causes vasoconstriction
Good for septic shock (vasodilatory shock not responsive to NOR)
Not good for hypovolemic or cardiogenic shock

Question 4

Epinephrine actions in anaphylaxis

Answer 4

Stabilizes mast cells and prevents degranulation (prevents propagation of distributive shock)
Vasoconstriction
Promotes inotropy and chronotropy
Bronchodilation

Question 5

Dobutamine

Answer 5

Good for increased CO in septic shock

Trade off is tachyarrhythmia and hypotension

Question 6

Ephedrine

Answer 6

Causes the release of preformed NOR granules

Direct effect on alpha and beta receptors

Question 7

Dopamine

Answer 7

Precursor to NOR
Acts on D1 and D2 receptors
Tachycardia and vasoconstriction
Only use it if you have nothing else