Shock Flashcards
Define shock
Inadequate perfusion of tissue with 02 rich blood
Define perfusion
The circulation of blood through an organ or tissue in amounts adequate to meet the body’s demand
What is another name for shock?
Hypovolemic shock
Why hemoglobin important?
Hemoglobin carries 02 to your cells. Binds to oxygen that is absorbed in the lungs and transports it to the tissues
Components of perfusion?
The pump, the fluid, the container
The heart, the blood, blood vessels. They are essential for circulation of oxygenated blood throughout the body
Define stroke volume
The amount of blood ejected by the heart in 1 contraction
Define preload
Volume of blood delivered to the atria prior to ventricular diastole
Defined afterload
Tension developed by the heart during contraction.
Resistance against which the left ventricle must pump and how much effort the ventricle must put forth to force blood into the systemic circulation
Atrial kick
Atrial kick occurs at the end of diastole.
Define frank starling mechanism
Law that states that the stroke volume of the heart increases in response to an increase in the volume of blood filling the heart
Define cardiac output? Formula? Factors that affect output?
The volume of blood moved by the heart in 1 minute
Stoke volume x heart rate
Stoke volume and heart rate directly affect cardiac output
3 layers of an artery?
Tunica adventitia, tunica media, tunica intima
What does tunica advenitia do?
Allows the arteries to stretch to prevent over expansion due to the pressure that is exerted on the walls by blood flow
What does tunica media do?
Controls the lumen size
What is tunica intima?
It is in intimate contact with the blood in the lumen
What kind of event is shock?
Shock is a cellular event
Where are baroreceptors located?
In the arch of the aorta, the carotid artery, and the kidneys
What are baroreceptors?
They respond to stretching of the arterial wall and manipulates BP. They are most sensitive to changes in BP. Cause vasoconstriction
Baroreceptors send a message to the brain stem and do what?
A message is related to the adrenal glands to secret epinephrine and norepinephrine into the bloodstream.
What are epinephrine and norepinephrine also known as? Where are they secreted and what do they interact with?
They are also known as catecholamines and are directly secreted into the blood stream. Eli and norepinephrine interact with alpha 1 and 2 and beta 1 and 2 receptors
What is a beta 2 receptor and where is it located?
It causes bronchodilation and located in the lung
In decompensated shock what do the kidneys do?
Kidneys stimulates the release of ADH/aldosterone (antidiuretic hormone) and increases the release of renin.
What is rouleaux and what happens?
The stacking of RBCs in misshapen chains which cause microemboli
What is the clotting process?
Vascular phase (vasoconstriction), platelet phase (agglutination and aggregation), coagulation (release of fibrin, clotting/scab, and dissolution of the clot
What is a transverse wound?
Wound is a clean cut, vessels constrict and draw inward
What is a longitudinal wound?
Constriction of smooth muscle, which enlarges wound because there is no vessel constriction which causes increased in blood loss. Ex, crushing trauma
What happens with aggressive fluid therapy?
Increases bp and can dislodge the clots, fluid dilutes body’s natural clotting factors
Where do baroreceptors send in pluses to?
The medulla aka vasomotor center
What nerve controls PNS?
The vagus nerve
What is a mechanism of shock?
Uncontrolled vasodilation
Types of distributive shocks?
Neurogenic, anaphylatic and septic shock
What does renin do and what is it released by?
It is a protein released into the bloodstream by the kidneys and responds to changes in BP to main cardiac output
What does aldosterone do?
Regulates sodium and potassium levels in the body to control blood pressure and the Balance of fluids and electrolytes
How does aldosterone work on the kidneys?
Increases sodium reabsorption into the mood to maintain cardiac output. Enhances potassium elimination in the urine (retains sodium) to raise BP