Shock

Question 1

Normal PT

Answer 1

11-12.5

Question 2

Normal PTT

Answer 2

30-40

Question 3

Normal fibrinogen

Answer 3

200-400

Question 4

Normal platelet

Answer 4

150,000-400,000

Question 5

sepsis continuum

Answer 5

infection + SIRS = sepsis

Question 6

severe sepsis

Answer 6

infection + SIRS + organ dysfunction

Question 7

septic shock

Answer 7

sepsis, including hypoperfusion despite fluid resuscitation
severe sepsis + hypotension unresponsive to 500-1,000 mL fluid challenge (SBP <90 or decreased more than 40 from baseline)

Question 8

criteria for sepsis-induced hypotension

Answer 8

SBP 40 from baseline in the absence of other causes of hypotension

Question 9

SIRS criteria

Answer 9

two or more of the following:

1. Temp 38.3 C
2. HR >90
3. Tachypnea (RR >20) or PaCO2 12,000; bands >10%

Question 10

*the sepsis cascade forms as a result of the loss of homeostasis leading to…

Answer 10

1. increased coagulation
2. increased inflammation
3. fibrinolysis

Question 11

minimum expectation for urine output (mL/hr)

Answer 11

0.5 mL/kg/hr

Question 12

Multiple Organ Dysfunction Syndrome (MODS)

Answer 12

progressive physiologic failure of 2 or more separate organs
presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained w/out intervention