Shigella Lawrence Flashcards

1
Q

Shigella

A
  • closely realted to E. coli

- important pathogen of people

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2
Q

Shigellosis is a common and serious disease in

A
  • monkeys

- dogs may excrete the organism after being infected by people, but they are resistant to disease

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3
Q

Shigella pathogenesis

A
  • invades and multiplies in intestinal cells
  • enters through M cells
  • Type III secretion system
  • invade and multiply in cytoplasm
  • Induse apoptosis if phagocytosed
  • Then go back
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4
Q

S. dysenteriae

A
  • can produce shiga toxin
  • local endothelial cells
  • 60S ribosomes and leads to inhibition of protein synthesis
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5
Q

Shigella disease

A

signs of fever, severe abdominal pain, and watery diarrhea

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6
Q

Edwardsiella ictaluri

A
  • enteric septicemia of channel catfish (ESC)
  • 22-28 C water
  • acute and chronic form
  • antimicrobial medicated feed
  • bacterin has limited effectiveness
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7
Q

Edwardsiella tarda

A

-opportunist sporadic infection in fish and mammals

-

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8
Q

Edwardsiella piscicida

A
  • enteric septicemia in catfish and hybrid catfish

- summer months with temperature > 80 F

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9
Q

Edwardsiella anguillarum

A

-eels in Japan/China

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