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oral histo > shedding of deciduous teeth > Flashcards

shedding of deciduous teeth Flashcards

1
Q

two generations of the human dentition

A

deciduous (primary) dentition
permanent (secondary) dentition

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2
Q

The physiologic process resulting in the elimination of the deciduous dentition

A

shedding or exfoliation

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3
Q

The shedding of deciduous teeth is the result of progressive?

A

resorption of the roots of teeth and their supporting tissue, the periodontal ligament.

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4
Q

resorption of the roots of the deciduous incisors and canines begins on their _____ surfaces

A

lingual

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5
Q

The cells responsible for the removal of dental hard tissue are identical to osteoclasts,

A

odontoclast

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5
Q

The cells responsible for the removal of dental hard tissue are identical to osteoclasts,

A

odontoclast

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6
Q

they are readily identifiable as large, multinucleated cells occupying resorption bays on the surface of a dental hard tissue.

A

odontoclast

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7
Q

They are smaller than osteoclast, contain fewer nuclei, and produce smaller resorption lacunae.

A

odontoclast

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8
Q

Their cytoplasm is vacuolated, and the surface of the cell adjacent to the resorbing hard tissue forms a ‘ruffled’ border

A

odontoclast

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9
Q

an extensive folding of the cell membrane into a series of invaginations 2 - 3um deep, with mineral crytallines within the depth of the invagination

A

ruffled border

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10
Q

peripheral to the ruffled border which it is devoid of organelled but rich in contractile proteins actin and myosin.

A

clean zone

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11
Q

it represents the attachment apparatus of the odontoclast

A

clear zone

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12
Q

odontoclast is characterized by?

A

high content of mitochondria and many vacuoles

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13
Q

T OR F: Deciduous teeth may be retained for a long time beyond their usual shedding schedule.
Such teeth are usually without permanent successors, or their successors are impacted.

A

TRUE

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14
Q

T OR F: If the permanent lateral incisor is missing, the deciduous tooth is often resorbed under
the pressure of the erupting permanent canine.

A

TRUE

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15
Q

what chemical activity occurs within the vacuoles of the odontoclast?

A

acid phosphate activity

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16
Q

T or F: odontoclast are able to resorb all the dental hard tissues, including enamel

A

TRUE

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17
Q

The monocyte, circulating in the blood, originally gives rise to all the different tissue ____ including the osteoclast

A

macropahges

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18
Q

odontoclast is derived from?

A

tartrate-resistant acid phosphatase (TRAP) - positive circulating monocytes

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19
Q

these cells were involved in
the differentiation, migration and activation of odontoclast and cementoblast like cells during resorption of deciduous teeth.

A

HLADR positive cells

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20
Q

The periodontal ligament cells in teeth undergoing
shedding express the tumor necrosis factor named?

A

RANKL
Receptor Activator of Nuclear factor Kappa B Ligand

21
Q

this expression is linked to odontoclast formation and activation of shedding process

A

RANKL expression

22
Q

odontoclast differentiation is promoted by _ and is inhibited by _

A

RANKL , OPG

23
Q

a decoy receptor that prevents RANKL from binding to RANK

A

OPG - osteoprotegrin

24
Q

most commonly found on surfaces of the roots in relation to the advancing permanent tooth.

A

odontoclast

25
Q

T or F: single-rooted teeth are usually shed before root
resorption is complete and in molars, the roots are usually completely resorbed and the crown is also partially resorbed, before exfoliation.

A

True

26
Q

the odontoblast layer is replaced by _____ which resorb both primary and secondary dentin

A

odontoclast

27
Q

give at least 3 similariries of odontoclast and osteoclast

A
  • Large multinucleated giant cell of variable shape
  • Occupy resorption bays or lacunae
  • Show ruffled border and clear zone peripheral to it
  • Cytoplasm adjacent to ruffled border shows high amounts of
    mitochondria and vacuoles
  • Acid phosphate activity within vacuoles
  • Process of resorption similar
  • Similar origin: from TRAP 1 circulating monocytes
  • Odontoclast differentiation promoted by RANKL and inhibited
    by OPG
28
Q

give 3 dissimilarities of odontoclast and osteoclast

A
  • Smaller and contain fewer nuclei
  • Produce smaller resorption bays
  • Resorb dental hard tissues: dentin, cementum and enamel
  • Seen, therefore on surfaces of dentin, cementum and enamel
    which are to be resorbed
  • Seen also in pulp chamber and root canal of resorbing deciduous teeth
29
Q

___ is achieved by cells resembling cementoblasts that lay down
a dense collagenous matrix in which spotty mineralization occurs

A

repair

30
Q

may be the cause for pathological root resorption

A

pressure excerted by tumors and cysts

31
Q

Unlike osteoblasts, ____ covering the root
are not responsive to hormones and cytokines.

A

cementoblasts

32
Q

odontoclast attaches to
the hard-tissue surface peripherally through the___

A

clear zone

33
Q

The membrane of the ruffled border acts as a proton pump, adding ___ to the extracellular environment and acidifying it so that mineral dissolution occurs.

A

hydrogen ions

34
Q

It is a common clinical observation that when a successional tooth germ is missing, shedding of the deciduous tooth is ___.

A

delayed

35
Q

As resorption of the roots initiated by pressure of the underlying tooth occurs, there is a progressive loss of surface area for attachment of the
___

A

periodontal ligament fiber bundles.

36
Q

_is involved with apoptotic cell death where shrinkage of cell can be phagocytozed by the neighboring cells

A

PDL

37
Q

Apoptotic cell death is a normal feature of ___ and is programed so that cells die
at specific times to permit orderly development.

A

EMBRYOGENESIS

38
Q

shedding is a programmed developmental event influenced by __

A

local factors

39
Q

The occurrence of apoptotic cell death in the resorbing periodontal ligament, in monozygotic twins the eruption pattern is largely how many %?

A

(80%)

40
Q

sometimes the roots of the deciduous teeth arent in the path of erupting permentent teeth and may escape resorption. they remain embedded in the jaw and are most frequently found in permanent premolars esp in lower second premoilar. They are cased in heavy laters of cellular celemtum

A

remnants of deciduous teeth

41
Q

the remnants of deciduous teeth are frequently found in__

A

lower second premolar

42
Q

the reason why there are remnents of deciduous teeth in molar

A

the roots of the lower second deciduous molar are strongly curved or divergent.

The mesiodistal diameter of the second premolars is much smaller than the greatest distance between the roots of the deciduous molar

43
Q

Deciduous teeth are retained for a long time beyond their usual shedding schedule. most often the upper lateral incisor

A

retained deciduous teeth

44
Q

teeth without permanent successors

A

retained deciduous teeth

45
Q

which tooth are affected in retained deciduous teeth

A

most frequent: upper
lateral incisor
less frequent: second
permanent premolar
rarely: lower central
incisor

46
Q

Eruption of the tooth ceases and becomes ankylosed to the bone of the jaw

A

submerged deciduous teeth

47
Q

They prevent the eruption of their permanent successors?

A

submerged deciduous teeth

48
Q

What are the factors that affect resorption/shedding?

A

Pressure, Masticatory Stress, Genetic Factors.

49
Q

This leads to trauma to the ligament and initiates resorption?

A

Masticatory Stress.

50
Q

Mechanism of Shedding?

A
  1. Resorption of primary tooth continues
  2. Root length decreases
  3. Surface area for attachment of PDL decreases
    4.Shedding/ExfoliationMasticatory Stress.
51
Q

Resorption of the roots of deciduous molars often first begins on what of their
surface?

A

inner surface

oral histo (2 decks)

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