SFM - Biochem Review Flashcards

1
Q

Rate Determining Enzyme -

Glycolysis

A

PFK 1

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2
Q

Rate Determining Enzyme -

Gluconeogenesis

A

Fructose 1,6 BP

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3
Q

Rate Determining Enzyme -

TCA Cycle

A

Isocitrate Dehydrogenase

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4
Q

Rate Determining Enzyme -

Glycogenolysis

A

Glycogen Phosphorylase

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5
Q

Rate Determining Enzyme -

HMP Shunt

A

G-6-PD

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6
Q

Rate Determining Enzyme -

Urea Cycle

A

Carbamoyl Phosphate Synthetase I

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7
Q

Rate Determining Enzyme -

Fatty Acid Synthesis

A

Acetyl-CoA Carboxylase

ACC

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8
Q

Rate Determining Enzyme -

Fatty Acid Oxidation

A

Carnitine Acyl Transferase I

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9
Q

Rate Determining Enzyme -

Ketogenesis

A

HMG - CoA Synthase

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10
Q

Rate Determining Enzyme -

Cholesterol Synthesis

A

HMG - CoA Reductase

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11
Q

Rate Determining Enzyme -

De novo PYRIMIDINE Synthesis

A

Carbamoyl Phosphate Synthetase II

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12
Q

Rate Determining Enzyme -

De novo Purine Synthesis

A

PRPP
Glutamine Phosphoribosyl-
pyrophosphate Amidotransferase

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13
Q

Positive Regulators of:

Glycolysis

A

AMP

Fructose 2,6 BP

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14
Q

Positive Regulators of:

Gluconeogenesis

A

Citrate

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15
Q

Positive Regulators of:

TCA Cycle

A

ADP

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16
Q

Positive Regulators of:

Glycogenesis

A

Glucose 6 P
Insulin
Cortisol

17
Q

Rate Determining Enzyme -

Glycogenesis

A

Glycogenesis Synthase

18
Q

Positive Regulators of:

Glycogenolysis

A

Epi
Glucagon
AMP

19
Q

Positive Regulators of:

HMP SHUNT

A

NADP+

20
Q

Positive Regulators of:

Urea Cycle

A

N-Acetylglutamate

21
Q

Positive Regulators of:

Fatty Acid Synthesis

A

Insulin

Citrate

22
Q

Positive Regulators of:

Fatty Acid Oxidation

A

NONE

23
Q

Positive Regulators of:

Ketogenesis

A

NO Pos or Neg

24
Q

Positive Regulators of:

Cholesterol Synthesis

A

Insulin
Thyroxine
Estrogen

25
Q

Positive Regulators of:

De novo PYRIMIDINE Synthesis

A

ATP

PRPP

26
Q

Positive Regulators of:

De novo PURINE Synthesis

A

NO Positive REGULATORS

27
Q

Negative Regulators of:

Glycolysis

A

ATP

Citrate

28
Q

Negative Regulators of:

Gluconeogenesis

A

AMP

Fructose 2,6 BP

29
Q

Negative Regulators of:

TCA Cycle

A

ATP

NADH

30
Q

Negative Regulators of:

Glycogenesis

A

EPI

Glucagon

31
Q

Negative Regulators of:

Glycogenolysis

A

Glucose 6 P
Insulin
ATP

32
Q

Negative Regulators of:

HMP SHUNT

A

NADPH

33
Q

Negative Regulators of:

Urea Cycle

A

NO NEG Regulators

34
Q

Negative Regulators of:

Fatty Acid Synthesis

A

Glucagon

Palmitoyl CoA

35
Q

Negative Regulators of:

Fatty Acid Oxidation

A

Malonyl CoA

36
Q

Negative Regulators of:

Ketogenesis

A

NO POS or NEG Regulators

37
Q

Negative Regulators of:

Cholesterol Synthesis

A

Glucagon

Cholesterol

38
Q

Negative Regulators of:

De novo PYRIMIDINE Synthesis

A

UTP

39
Q

Negative Regulators of:

De novo PURINE Synthesis

A

AMP
GMP
IMP (inosine monophosphate)