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SMP Block 2 > SFII Immunology > Flashcards

SFII Immunology Flashcards

1
Q

What cell can activate a naive T cell?

A

Dendritic cell (DC)

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2
Q

Interleukins aka?

A

Cytokines

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3
Q

What cells are found in the lymph node cortex?

A

B cells

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4
Q

What cells are found in the lymph node paracortex?

A

T cells

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5
Q

What cells are found in the lymph node inner medulla?

A

Plasma and macrophages

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6
Q

B cell progenitor lineage

A

Lymphoid

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7
Q

T cell progenitor lineage

A

Lymphoid

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8
Q

Dendritic cell progenitor lineage

A

Both

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9
Q

Granulocyte progenitor lineage

A

Myeloid

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10
Q

Platelet progenitor lineage

A

Myeloid

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11
Q

Erythrocyte progenitor lineage

A

Myeloid

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12
Q

Monocyte progenitor lineage

A

Myeloid

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13
Q

What is the function of CCR7?

A

Chemokine that sends DC to lymph nodes to activate naive T cells

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14
Q

MHC I responds to

A

Cytosolic pathogen - virus / malignant cells

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15
Q

MHC II responds to

A

Extracellular pathogen - bacteria

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16
Q

MHC I activates which T cells?

A

CD8

17
Q

MHC II activates which T cells?

A

CD4

18
Q

Stem cell CDs

A

31, 34

19
Q

Leukocyte CDs

A

45

20
Q

Granulocyte CDs

A

15, 24, 45, 114, 182

21
Q

Monocyte CDs

A

11a, 14, 45, 91, 114

22
Q

T lymphocyte CDs

A

3, 45

23
Q

T helper CDs

A

3, 4, 45

24
Q

T regulatory CDs

A

FOXp3, 4, 25

25
Q

Cytotoxic T CDs

A

3, 8, 45

26
Q

B lymphocyte CDs

A

19, 20, 24, 45

27
Q

Thrombocyte CDs

A

45, 61

28
Q

NK CDs

A

3, 16, 30, 31, 56

29
Q

Do T or B cells respond to epitome alone?

A

B

30
Q

Do T or B cells respond to epitome with MHC?

A

T

31
Q

TH1 function

A

Macrophage-mediated destruction of intracellular pathogens

32
Q

TH2 function

A

IgE for parasite destruction

33
Q

TH17 function

A

Neutrophil recruitment (bacterial infection)

34
Q

TFH function

A

Stimulate antibodies from B cells

35
Q

Treg cell function

A

Suppress T cell response

SMP Block 2 (4 decks)

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