Sexually Transmitted Infections Flashcards

1
Q

Why is gonorrhoea more common in men than women?

A

Gonorrhoea is an infection that is associated with frequent changing of partners

This is a behaviour seen in MSM population

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2
Q

What is the name of the pathogen that causes Chlamydia?

What type of pathogen is it?

A

Chlamydia trachomatis

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3
Q

What is the name of the pathogen that causes Gonorrhoea?

A

Neisseria gonorrhoea

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4
Q

In adults, where do C. trachomatis and N. gonorrhoea infect?

A
Urethra
Endocervical canal
Rectum
Pharynx
Conjuctiva
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5
Q

In neonates, where do C. trachomatis and N. gonorrhoea infect?

A

Conjuctiva

Pneumonia with C. trachomatis is sometimes seen too

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6
Q

Symptoms of C. trachomatis and N. gonorrhoea infections in men?

A

Asymptomatic

Dysuria
Urethral discharge

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7
Q

What are some complications that men infected with C. trachomatis get?

A

Epididymo-orchitis

Reactive arthritis

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8
Q

Symptoms of C. trachomatis and N. gonorrhoea infections in women?

A

Asymptomatic

Discharge
Menstrual irregularity
Dysuria

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9
Q

What are some complications that women with C. trachomatis and N. gonorrhoea infections get?

A

Pelvic inflammatory disease

Neonatal transmission

Fitz-Hugh-Curtis Syndrome

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10
Q

What is Pelvic inflammatory disease?

A

Infection of the female upper genital tract, uterus, fallopian tube, ovaries

Caused by Chlamydia and Gonorrhea

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11
Q

What problems does pelvic inflammatory disease cause for women?

A

Infertility
Ectopic pregnancies
Chronic pelvic pain

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12
Q

What is Fitz-High-Curtis syndrome?

A

Inflammation of the liver capsule resulting from Pelvic inflammatory disease

Causes adhesions

Caused by Chlamydia and Gonorrhoea

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13
Q

How can you tell by looking at the discharge, whether n infection is caused by C. trachomatis or N. gonorrhoea?

A

In gonorrhoea the discharge is more prominent, it is white and their is more of it

In Chlamydia it is less offensive

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14
Q

C. trachomatis is an extra-cellular bacteria. True or false?

A

False

It is intracellular

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15
Q

How can you test for chlamydia?

A

Female:

  • endocervical swab
  • self-collected vaginal swab
  • first void urine

Male:
- first void urine

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16
Q

Once you have received a sample from a patient suspected of having Chlamydia or Gonorrhoea, what do you do to it to check if it is either one of these?

A

Nucleic acid amplification tests

Create many copies of the bacterial DNA so you can analyse them and confirm the pathogen

17
Q

What is NAAT?

A

Nucleic acid amplification test

Used to diagnose C. trachomatis and N. gonorrhoea infections

18
Q

Management of Chlamydia?

A

Trace contacts
Test for other STIs

Azithromycin
Doxycycline

Erythromycin in pregnancy

19
Q

Which infection, Chlamydia or Gonorrhoea, are we more concerned about antibiotic resistance?

A

Gonorrhoea
It is very good at acquiring resistance from other organisms

Chlamydia is intracellular so there are no concerns there

20
Q

How can you test for Gonorrhoea?

What is it important to remember when dealing with samples with potential gonorrhoea infections?

A

Swab from male urethra or female endocervix

Use NAAT

You need to keep the samples warm or the bacteria will die

21
Q

Management of Gonorrhoea?

A

Contact tracing
Test for other STIs

Single dose: ceftriaxone injection PLUS azithromycin

22
Q

What is the name for the condition which neonates get affecting their eyes, caused by C. trachomatis and N. gonorrhoea?

A

Chlamydial or Gonococcal

Ophthalmia

23
Q

Which infection, Chlamydia or Gonorrhoea is more associated with multiple sexual partners?

A

Gonorrhoea

24
Q

Which pathogen causes Syphilis?

What type of pathogen is it?

A

Treponema pallidum

Bacteria

25
Q

There are 2 stages of Syphilis infection, name them?

A

Early: within 2 years of infection

Late: over 2 years

26
Q

Syphilis is only transmissible via vaginal and anal sex.

True or false?

A

False, oral sex too

27
Q

What phases are seen within early Syphilis infection?

A

Primary
Secondary
Early latent

28
Q

What would you see in primary Syphilis?

A

A chancre (a painless ulcer) seen on genitals, mouth

Gets better on its own

29
Q

What would you see in secondary Syphilis?

A

Multi-system disease

  • skin rash
  • mucous membrane lesions
  • bone pain
  • alopecia
30
Q

What is a chancre?

A

A painless ulcer seen in cases of Syphilis

31
Q

What is the difference in the way that these diseases are passed onto a neonate:

  • Chlamydia
  • Gonorrhoea
  • Syphilis?
A

C & G = passed during birth, as baby goes through the birth canal bacteria colonise the baby

S = can be passed across the placenta

32
Q

What complications can arise from Syphilis infections?

A

Gummatous growths

Neurosyphilis

  • strokes
  • dementia

CVS:
- aneurysms of a. aorta

33
Q

What are gummatous growths?

A

Soft, non-cancerous growth that can occur in liver, brain, skin etc.

They have necrotic cores surrounded by inflammatory tissue

They can cause deformities to the face if found on the skin

34
Q

Diagnosis of syphilis?

A

Serology

- take a sample from a genital ulcer or from a rash

35
Q

Management of Syphilis?

A

Contact tracing
Test for other STIs
Penicillin injection