Sexually Transmitted Diseases Flashcards
Primary or secondary infection in preg mom is worse?
primary cause no IgG
how to test for infections like viruses?
serology
If a serology report against ‘x’ is negative what could it mean?
- not exposed
- haven’t mounted response
- viral incubation period
IgM +ve means?
- depends if you can compare to a previous result
- lasting is variable
CMW IgM lasts?
3-18 months to 4 years…
+ve IgG means?
past infection or vaccination
what happens if you can’t get rising titres?
Avidity of Antibodies
Epstein Barr virus could do what to serology?
polyclonal B-cell response with glandular fever, range of antibodies produced
if positive result for virus in preg, could mean 2 things:
- protective for future preg (eg/ rubella)
2. not protective, chronic (HIV)
What kind of bug is toxoplasma gondii?
protozoa
Signs of Parvo B19?
slapped cheek
maculopapular rash
Parvo does what to body?
decreases reticolocyte lifespan: anaemia
Rubella management in preg?
Termination if high risk fetal morbidity
CMV treatment?
Gancyclovir or termination
Varicella in first trimester as primary infection results?
limb hypoplasia, microcephaly, cataracts, mental
CMV in preg, results in affected fetus?
hearing, visual, psychomotor defects
treatment for toxoplasmosis in preg woman?
macrolide
Rubella greatest damage when?
first trimester
Parvo in fetus? how treat?
Hydrops Foetalis
Intrauterine transfusion
HSV on fetus?
HSV sepsis syndrome
often fatal
HSV treatment and management?
Acyclovir for mom for suppression
C-section to avoid perinatal
Why test for syphilis in woman who had sex with man with gonorrhoea?
chances are that man who had gonorrhoea had sex with another man, may have syphilis or HIV so test for syphilis/HIV in absence of other info
Gonorrhoea look how under microscopy?
gram -ve diplococci inside neutrophils
see big purple oval under microscopy from cervical swab?
Candida Albicans
Gonorhoea management?
3rd gen cefixime
Chlamydia treatment?
Azithromycin (macrolide)
syphilis treatment?
penicillin
Candida Albicans treatment?
antifungal: amphotericin
Presence of hepatitis Be (HBe) antigen and absence of HBe antibody usually indicates?
active hepatitis B virus (HBV) replication and high infectivity
-ve Hep B Core antibody means?
no infection within last 6/12
+ve Hep B Core antibody means?
recent acute hepatitis B infection
Absence of HBe antigen with appearance of HBe antibody is?
loss of HBV infectivity
Monospot test for glandular fever: which virus?
EBV -polyclonal B cells, sheep RBCs
CMV worse when?
primary infection in mom
