Sexually Transmitted Disease (Bacteria causes)

Question 1

In Bacterial Vaginosis (BV):
a. BV can be diagnosed by PCR
b. Clue cells support the diagnosis
c. The whiff test is positive
d. The pH of the vaginal secretions is increased to >4.5
e. BV is associated with increased transmission of HIV

Answer 1

a. T
b. T
c. T
d. T
e. T

Question 2

In a person with a genital ulcer:
a. Consider HPV
b. Do HSV serology
c. Do HSV PCR
d. Do a syphillis EIA

Answer 2

a. F (HPV presents as genital warts)
b. F (serology is positive even if there was past infection)
c. T
d. T

Question 3

In an infection with Chlamydia trachomatis:
a. Culture is more sensitive than PCR
b. Infection in women may be asymptomatic
c. C. trachomatis causes epididymitis in men
d. Urine can be used for a PCR Test

Answer 3

a. F (More specific, less sensitive)
b. T
c. T
d. T (Midstream urine)

Question 4

In gonorrhoea,
a. A urethral Gram stain is helpful in men
b. Urine can be used for a PCR Test
c. Blood agar is the best agar for culture of vaginal swabs
d. It may be found in rectal and throat samples

Answer 4

a. T
b. T
c. F
d. T

Question 5

Mycoplassma genitalum
a. Causes urethritis
b. Is diagnosed by culture
c. Shows resistance to both macrolides and quinolones
d. Can be treated with Amoxicillin

Answer 5

a. T
b. F (diagnosed by nucleic acid tests)
c. T
d. F (mycoplasma has no peptidoglycan, and hence cannot be affected by amoxicillin)

Question 6

In a person with an STD
a. Test for HIV
b. Test for HBV
c. Test for syphillis
d. Trace contacts

Answer 6

a. T
b. T
c. T
d. T

Question 7

Case-based:

22 yr old male gym instructor, with penile discharge and dysuria. An STD screen shows:
a. Gram stain - Gram negative, intracellular diplococci
b. PCR for GC (Gonorrhoea)/ CT (Chlamydia) - both positive
c. Serology -
Syphillis - EIA neg
HIV - neg
HBV SAg - neg

Answer 7

Gonorrhoea with Chlamydia

Question 8

Case-based:

A 42 yr old female with smelly vaginal discharge. An STD screen shows:
a. Gram stain - clue cells present
b. PCR for GC (Gonorrhoea)/ CT (Chlamydia) - negative
c. Whiff Test - positive
d. Serology -
Syphilis - EIA neg
HIV - neg
HBV SAg - neg

Answer 8

Bacterial Vaginosis (Likely Gardatella spp. bacteria)

Question 9

Case-based:

A 38 yr old female attends a contact clinic. Her new boyfriend has developed dysuria. An STD screen shows:
a. Gram stain - not done
b. PCR for GC (Gonorrhoea)/ CT (Chlamydia) - pos for CT
c. Serology -
Syphillis - EIA neg
HIV - neg
HBV SAg - neg

Answer 9

Chlamydia

Question 10

Case-based:

55 yr old male golf player has painful penile blisters, some have ulcerated. An STD screen shows:
a. Gram stain - not done
b. PCR for GC (Gonorrhoea)/ CT
(Chlamydia) - negative
c. HSV PCR - pos
d. Serology -
Syphillis - EIA pos
HIV - pos
HBV SAg - pos

Answer 10

HIV + active HSV infection (Herpes Simplex)

Question 11

Case-based:

25 yr old female complains of vaginal itchiness and discharge. It irritates on passing urine. She has a UTI treated last week. An STD screen shows:
a. Gram stain - clue cells NOT seen
b. PCR for GC (Gonorrhoea)/ CT (Chlamydia) - negative
c. HSV PCR - neg
d. Candida POCT - positive
e. Whiff Test - neg
f. Serology -
Syphillis - EIA neg
HIV - neg
HBV SAg - neg

Answer 11

Candida infection