Sexually-Transmitted and Vesiculobullous Diseases

Question 1

Symmetrical, generalized, maculopapular eruptions, polymorphous, usually over the face, shoulders, flanks and palms and soles with scaling, with suggestive sexual history, painless genital ulcer

Answer 1

Secondary syphilis

Question 2

Papular lesions located on folds of moist skin usually around genitals and anus, may become hypertrophic, forming soft red mushroom-like mass, moist weeping gray surface

Answer 2

Condylomata lata

Question 3

Most frequent manifestation of orolabial herpes

Answer 3

Fever blister or cold sore

Question 4

Dew drop on rose petal, teardrop on an erythematous base, starting with macules progressing to vesicles pustules and crusting, examination of lesions show different ages of healing usually starting on the trunk spreading centripetally outward

Answer 4

Varicella

Question 5

Erythema, papules and plaques initially, mild pain a few days before, subsequently developing vesicles and blisters following a dermatomal distribution, painful

Answer 5

Herpes zoster

Question 5

Most common complication of varicella

Answer 5

Secondary bacterial
infection

Question 6

Vesicles on the side and tip of nose indicative of ophthalmic zoster

Answer 6

Hutchinson’s sign

Question 7

Large tense blisters on flexor surfaces, groin axillae, and trunk, subepidermal blister, anti-hemidesmosome antibodies (Bullous pemphigoid antigens), linear IF pattern

Answer 7

Bullous pemphigoid

Question 7

Involvement of the facial and auditory nerves by varicella zoster virus

Answer 7

Ramsay-Hunt syndrome

Question 8

Suprabasal blisters, anti-desmosome (desmogleins) antibodies, lace-like IF pattern

Answer 8

Pemphigus vulgaris

Question 9

Papules, vesicles and pustules with honey-colored crusts

Answer 9

Impetigo contagiosa

Question 10

Variant of impetigo, inadequately treated leading to punched out ulcerative lesions

Answer 10

Ecthyma